球形嚢破裂を伴った病理組織学的メニエ-ル病 (メニエ-ル病の研究-6-<特集>)

概要

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Both of the temporal bones of a 52-year-old man who died of a metastatic cancer of the stomach were histologically studied. One year prior to death, he had stayed in bed for 3 days suffering from a severe vertiginous attack. His left temporal bone showed collapse of the cochlear duct and rupture of the saccular wall. The deficit of the saccular membrane affected almost half of the entire membrane. The distension of the Reissner membrane indicated the presence of endolymphatic hydrops before the occurrence of its collapse. The rupture of the saccular membrane was considered to be caused by rapid increase in endolymph within the saccule, resulting in collapse of the cochlear duct. Though these pathological findings resemble those of Meniere's disease, this patient failed to be so diagnosed because of the lack of repetition of vertigo, which may have been due to a persistent endolymphatic fistula in the saccule. The right ear of this patient had a normal cochlear duct and saccule.
耳鼻咽喉科臨床学会の論文