Rare Primary Effusion Lymphoma Associated with HHV-8 in Japan
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概要
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We describe a 62-year-old man infected with human immunodeficiency virus (HIV)-1 who developed primary effusion lymphoma (PEL). Pleural effusion contained atypical lymphoid cells with human herpesvirus (HHV)-8 latent nuclear antigen (LANA)+. Radiological examination revealed pleural and pericardial effusion, but no evidence of tumor mass or lymph node enlargement. The patient was administered with highly active anti retroviral therapy (HAART) and THP-COP therapy, resulting in complete remission. The prevalence of HHV-8 infection among HIV positive individuals is higher than in the general population in Japan. Although PEL is extremely rare in Japan, the incidence might increase in the future.
著者
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Ogata Masao
Department Of Basic Science Graduate School Of Arts And Science University Of Tokyo
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Amemiya Yuka
Department of Internal Medicine 2, Oita University Faculty of Medicine
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Hiramatsu Kazufumi
Department of Infectious Diseases, Oita University Faculty of Medicine
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Ikebe Taichi
Department of Hematology, Oita University Faculty of Medicine
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Saburi Masuho
Department of Hematology, Oita University Faculty of Medicine
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Ando Takeaki
Department of Hematology, Oita University Faculty of Medicine
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Kadota Junichi
Department of Hematology, Oita University Faculty of Medicine
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Saburi Masuho
Department of Internal Medicine 2, Oita University Faculty of Medicine
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Kadota Junichi
Department of Internal Medicine 2, Oita University Faculty of Medicine
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Kohno Kazuhiro
Department of Hematology, Oita University Faculty of Medicine
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Kohno Kazuhiro
Department of Internal Medicine 2, Oita University Faculty of Medicine
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Hiramatsu Kazufumi
Department of Internal Medicine 2, Oita University Faculty of Medicine
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