Simultaneous Dissolution of Naproxen and Flurbiprofen from a Novel Ternary γ-Cyclodextrin Complex
スポンサーリンク
概要
- 論文の詳細を見る
A crystalline ternary complex was prepared by sealed-heating of naproxen (NPX) with a flurbiprofen (FBP)/γ-cyclodextrin (γ-CD) inclusion complex. The dissolution rates of NPX and FBP in the ternary complex were almost the same, indicating that FBP and NPX from the complex dissolved simultaneously. The ternary CD complex showing a fascinating dissolution property could be a new formulation for combination therapies.
- 公益社団法人 日本薬学会の論文
著者
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Higashi Kenjirou
Graduate School of Pharmaceutical Sciences, Chiba University
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Limwikrant Waree
Graduate School of Pharmaceutical Sciences, Chiba University
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Moribe Kunikazu
Graduate School Of Pharmaceutical Sciences Chiba University
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Yamamoto Keiji
Graduate School Of Pharmaceutical Sciences Chiba University
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Ideura Saori
Graduate School of Pharmaceutical Sciences, Chiba University
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Waraya Haruka
Graduate School of Pharmaceutical Sciences, Chiba University
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Higashi Kenjirou
Graduate School Of Pharmaceutical Sciences Chiba University
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Moribe Kunikazu
Graduate School Of Pharmaceutical Sciences Chiba Univ.
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