Alcohol consumption and mortality in Japan : the Miyagi cohort study
スポンサーリンク
概要
- 論文の詳細を見る
BACKGROUND: We examined the association between alcohol consumption and all-cause mortality in Japanese men and women.METHODS: From June through August 1990, a total of 39,076 subjects (20,660 men and 18,416 women) in 14 municipalities of Miyagi Prefecture in rural northern Japan (40-64 years of age) completed a self-administered questionnaire that included information about alcohol consumption and various health habits. During 11 years of follow-up, we identified 1,879 deaths (1,335 men and 544 women). We used Cox proportional-hazards regression to estimate relative risk (RR) of all-cause mortality according to categories of alcohol consumption and to adjust for age, education, marital status, past histories of chronic diseases, body mass index, smoking, walking and dietary variables.RESULTS: Among men, the risk for all-cause mortality was significantly higher in past drinkers than never-drinkers (multivariate RR, 1.86; 95% confidence interval [CI], 1.50-2.29). There was a dose-response association between alcohol consumption and the risk of all-cause mortality among current drinking men: multivariate RRs in reference to never-drinkers (95% CI) were 1.10 (0.90-1.33), 1.17 (0.96-1.42), 1.16 (0.96-1.40), and 1.62 (1.32-1.99) in current drinkers who consumed less than 22.8 g, 22.8-45.5 g, 45.6-68.3 g, and 68.4 g or more alcohol per day, respectively (P for trend<0.001). Similar association was observed among women (P for trend=0.005).CONCLUSIONS: The results indicated that alcohol consumption tended to be associated with linear increase in risk of all-cause mortality among Japanese men and women, and the association was remarkable for younger men.
- Japan Epidemiological Associationの論文
著者
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NISHINO Yoshikazu
Division of Epidemiology, Miyagi Cancer Center Research Institute
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TSUBONO Yoshitaka
Division of Health Policy, Tohoku University School of Public Policy
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TSUJI Ichiro
Division of Epidemiology, Department of Public Health and Forensic Medicine, Graduate School of Medi
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OHKUBO TAKAYOSHI
Division of Public Health, Tohoku University School of Medicine
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HISAMICHI SHIGERU
Division of Public Health, Tohoku University School of Medicine
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FUKAO Akira
Department of Public Health, Yamagata University School of Medicine
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KURASHIMA Kayoko
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Gradu
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Nakaya N
Division Of Epidemiology Department Of Public Health And Forensic Medicine Tohoku University Graduat
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Kurashima Kayoko
Division Of Epidemiology Department Of Public Health And Forensic Medicine Tohoku University Graduat
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大久保 孝義
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Gradu
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Yamaguchi Junko
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Gradu
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Shibuya Daisuke
Miyagi Cancer Society
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Fukudo Shin
Department of Behavioral Medicine, Tohoku University Graduate School of Medicine
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Fukudo Shin
Department Of Behavioral Medicine Tohoku University Graduate School Of Medicine
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Tsubono Yoshitaka
Division Of Breast Surgery Saitama Cancer Center
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Tsuji Ichiro
Division Of Epidemiology Department Of Public Health And Forensic Medicine Tohoku University Graduat
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Nishino Yoshikazu
Division Of Epidemiology Department Of Public Health And Forensic Medicine Tohoku University Graduate School Of Medicine
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Fukao Akira
Department Of Public Health Graduate School Of Medical Science Yamagata University
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Hisamichi Shigeru
Division Of Epidemiology And Prevention Aichi Cancer Center Research Institute
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Kurashima Kayoko
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine
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Tsubono Yoshitaka
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine
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Yamaguchi Junko
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine
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Nishino Yoshikazu
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine
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Hisamichi Shigeru
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine
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Ohkubo Takayoshi
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine
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Nakaya Naoki
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine
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