Impact of Non-dietary Nutrients Intake on Misclassification in the Estimation of Nutrient Intake in Epidemiologic Study

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概要

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• BACKGROUND: Few previous epidemiologic studies have evaluated the effects of non-dietary nutrient intake, such as supplements, over the counter (OTC) drugs, and prescription drugs containing vitamins or minerals, in examining the relationship between dietary factors and health outcomes.METHODS: To examine the influence of the non-dietary intake of vitamins and calcium on the estimation of nutrient intake, we conducted a cross-sectional study with 1,168 community-dwelling Japanese subjects aged 70 years or older in 2002. The subjects were asked to bring their non-dietary nutrient sources to the examining site. The dietary and non-dietary intakes of vitamins B1, C, E and calcium were obtained and the subjects were grouped into quartiles according to their dietary intake and their dietary plus non-dietary intake. The degree of agreement between these two classifications was examined to estimate the degree of misclassification.RESULTS: Among the subjects who were classified into the highest intake category for vitamin E with dietary intake plus non-dietary nutrient intake, 34.2 % were misclassified into lower category with dietary intake alone. Similarly, intake of vitamin B1, vitamin C and calcium were misclassified 28.8%, 18.8 %, 6.2 %, respectively.CONCLUSIONS: Our data suggest that estimation of vitamin intake from dietary sources alone would yield a maximum misclassification of one-third, which would lead to misleading conclusions being drawn from epidemiologic studies. In contrast, the degree of misclassification for calcium may be relatively small.J Epidemiol 2006; 16: 193-200.

• 日本疫学会の論文
• 2006-09-01

著者

• Haketa Akira

  日本大学 医学部内科学系腎臓高血圧内分泌内科

• Nakaya N

  Division Of Epidemiology Department Of Public Health And Forensic Medicine Tohoku University Graduat

• Nakaya Naoki

  東北大学 医学系研究科運動学分野

• Nakaya Naoki

  Psycho-oncology Division Research Center For Innovative Oncology National Cancer Center Hospital Eas

• Nakaya Naoki

  Psycho-oncology Division National Cancer Center Research Institute East

• Nakaya Naoki

  Division Of Epidemiology Departments Of Public Health And Forensic Medicine Tohoku University Gradua

• Hozawa A

  Division Of Epidemiology Department Of Public Health And Forensic Medicine Tohoku University Graduat

• Hozawa Atsushi

  東北大学 医学系研究科運動学分野

• Tsuji I

  Division Of Epidemiology Department Of Public Health And Forensic Medicine Tohoku University Graduat

• Tsuji Ichiro

  東北大学 医学系研究科運動学分野

• Kuriyama Shinichi

  東北大学 医学系研究科循環器病態学

• Kuriyama Shinichi

  Division Of Epidemiology Department Of Public Health & Forensic Medicine Tohoku University Gradu

• Ohnuki K

  Division Of Breast Surgery Iwate Prefecture Central Hospital

• Ohmori Kaori

  東北大学 医学系研究科公衆衛生学

• Ohmori-matsuda Kaori

  東北大学 医学系研究科運動学分野

• Ohmori Kaori

  Department Of Public Health And Forensic Medicine Tohoku University Graduate School Of Medicine And

• OGATA Mikiko

  The Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University G

• KURIYAMA Shinichi

  The Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University G

• SATO Yuki

  The Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University G

• SHIMAZU Taichi

  The Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University G

• NAKAYA Naoki

  The Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University G

• OHMORI Kaori

  The Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University G

• HOZAWA Atsushi

  The Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University G

• TSUJI Ichiro

  The Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University G

• OHNUKI Koji

  Second Department of Surgery, Tohoku University School of Medicine

• Ogata Mikiko

  The Division Of Epidemiology Department Of Public Health And Forensic Medicine Tohoku University Gra

• Tsuji Ichiro

  東北大学 医学系研究科循環器病態学

• Hara Azusa

  東北大学 臨床薬学

• Shimazu Taichi

  Division Of Epidemiology Department Of Public Health And Forensic Medicine Tohoku University Graduat

• Ohnuki Koji

  Second Department Of Surgery Tohoku University School Of Medicine

• Sato Yuki

  The Division Of Epidemiology Department Of Public Health And Forensic Medicine Tohoku University Gra

• Sugawara Yumi

  Division Of Epidemiology Department Of Public Health And Forensic Medicine Tohoku University Graduat

• Kanemura Seiki

  Division Of Epidemiology Department Of Public Health And Forensic Medicine Tohoku University Graduat

• Hozawa Atsushi

  Department Of Public Health And Forensic Medicine Tohoku University Graduate School Of Medicine And

• Tsuji Ichiro

  Division Of Epidemiology Department Of Public Health And Forensic Medicine Tohoku University Graduat

• Kuriyama Shinichi

  東北大学 医学系研究科公衆衛生学

• Ishida Tsunehiro

  Division Of Epidemiology Department Of Public Health And Forensic Medicine Tohoku University Graduat

• Kuriyama Shinichi

  Division Of Epidemiology Tohoku University Graduate School Of Medicine

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