Effects of a Water-Soluble Bioactive Factor from Grifola frondosa, the Mushroom Maitake on Adipocyte Differentiation
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概要
- 論文の詳細を見る
A bioactive factor inhibiting adipocyte differentiation was found in the water-soluble fraction of Maitake (Grifola frondosa). The fraction including bioactive factors was isolated by HPLC on Superdex Peptide HR 10/30. This water-soluble fraction was found to inhibit the differentiation of adipocytes as determined by the decrease in the glycerol-3-phosphate dehydrogenase (GPDH) activity, triglyceride (TG) accumulation and leptin levels. Furthermore, this factor inhibited the expression of peroxisome proliferator activated receptor γ(PPARγ), one of the master regulators expressed early in adipocyte differentiation cascades. Thus, this bioactive factor may act on the expression of some factors at earlier stages leading to the expression of PPARγ.
- 社団法人 日本食品科学工学会の論文
- 2004-11-01
著者
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MINAMINO Katsuhiko
Department of Food Science and Nutrition, School of Human Environmental Science, Mukogawa Women's Un
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OHTSURU Masaru
Department of Food Science and Nutrition, School of Human Environmental Science, Mukogawa Women's Un
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Ohtsuru Masaru
Department Of Food Science And Nutrition School Of Human Environmental Science Mukogawa Women's
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Minamino Katsuhiko
Department Of Food Science And Nutrition School Of Human Environmental Science Mukogawa Women's
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MASUI Hironori
Department of Food and Life Science, Yamaguchi Prefectural University
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Masui Hironori
Department Of Dietary Life And Food Science Mukogawa Women's University Junior College Division
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Masui Hironori
Department Of Food Science And Nutrition School Of Human Environmental Science Mukogawa Women's
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YANAGA Yuri
Department of Food Science and Nutrition, School of Human Environmental Science, Mukogawa Women's Un
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Yanaga Yuri
Department Of Food Science And Nutrition School Of Human Environmental Science Mukogawa Women's
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OHTSURU Masaru
Department of Food and Nutrition, Yamaguchi Womens University
関連論文
- A Water-Soluble Extract from Grifola frondosa, Maitake Mushroom, Decreases Lipid Droplets in Brown Adipocyte Tissue Cells
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- Effects of a Water-Soluble Bioactive Factor from Grifola frondosa, the Mushroom Maitake on Adipocyte Differentiation
- Effect of Maitake (Grifola frondosa) Water Extract on Inhibition of Adipocyte Conversion of C3H10T1/2B_2C_1 Cells
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