Corn Silk Induced Cyclooxygenase-2 in Murine Macrophages
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概要
- 論文の詳細を見る
Stimulation of murine macrophages with corn silk induced cyclooxygenase (COX)-2 with secretion of PGE2. Expression of COX-2 was inhibited by pyrolidine dithiocarbamate (PDTC), and increased DNA binding by nuclear factor kappa B (NF-κB), indicating that COX-2 induction proceeds also via the NF-κB signaling pathway. A specific inhibitor of COX-2 decreased the expression level of inducible nitric oxide synthase (iNOS) stimulated by corn silk. PGE2 elevated the expression level of iNOS, probably via EP2 and EP4 receptors on the surface of the macrophages.
- 2005-10-23
著者
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Kim Kyung
Department Of Genetic Engineering Kyungpook National University
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Choi Sang
Department Of Physics Korea University
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Kim Kyung
Department Of Biological Sciences And The Immunomodulation Research Center University Of Ulsan
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CHOI Hye-Seon
Department of Biological Sciences and Immunomodulation Research Center, University of Ulsan
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Kim Kyung
Department Of Anesthesia And Pain Medicine School Of Medicine Pusan National University
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SHIN Hyun-Hee
Department of Biological Sciences and the Immunomodulation Research Center, University of Ulsan
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Choi Sang
Department Of Food Science And Nutrition Catholic University Of Daegu
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Choi Hye-seon
Department Of Biological Sciences (bk21 Program) And Immunomodulation Research Center University Of
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Choi Hye-seon
Department Of Biological Sciences And The Immunomodulation Research Center University Of Ulsan
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Shin Hyun-hee
Department Of Biological Sciences And The Immunomodulation Research Center University Of Ulsan
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Choi Sang
Department Of Biological Sciences And The Immunomodulation Research Center University Of Ulsan
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Choi Sang
Department Of Agricultural Chemistry Gyeongsang National University
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