Changes in salivary stress markers under experimental xerostomia in the rat
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概要
- 論文の詳細を見る
Saliva sampling has the advantages of being easy, stress free and non-invasive, allowing for multiple sampling. We examined how xerostomia that was induced by botulinum toxin A treatment affected the salivary cortisol and amylase levels, and compared the characteristics of these parameters. Twenty male Wistar rats weighing 280-320g were used in this experiment. After botulinum toxin A treatment, the stress response was determined using salivary cortisol and amylase levels during chorda-stimulation. The amylase level was significantly decreased on day 7 after botulinum toxin A was administered. However, the cortisol level was increased, and the increase was to a lesser extent than that of amylase. Both the salivary cortisol and amylase levels recovered over time, suggesting that they are good indices of xerostomia. Furthermore, it is suggested that amylase is an index of relaxation.
- 大阪歯科学会の論文
著者
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Uchihashi Kenji
Department of Physiology, Osaka Dental University
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Tsuji Yoichi
Department Of Physiology Osaka Dental University
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Tsuji Yoichi
Department Of Electrical & Electronics Engineering Ashikaga Institute Of Technology
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Uchihashi K
Department Of Physiology Osaka Dental University
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Uchihashi Kenji
Department Of Physiology Osaka Dental University
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Nishikawa Yasuo
Department Of Physiology Osaka Dental University
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Nishikawa Yasuo
Department Of Physiology Osaka Dental Univeristy
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Nishikawa Yasuo
Osaka Dental Univ. Osaka Jpn
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Nishikawa Yasuo
Department of Electronic Engineering, Faculty of Engineering, Tokyo Institute of Polytechnics,
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Uchihashi Kenji
Department of Physiology and Graduate School of Dentistry, Osaka Dental University
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