病理診断アトラス(13) : 内分泌腫瘍2:副腎皮質と髄質・傍神経節・異所性ホルモン産生腫瘍ほか

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The previous article (part 1) has dealt with pathology of pituitary tumors, thyroid carcinomas, and parathyroid tumors. This article first describes adrenocortical adenomas and primary hyperplasia causing primary aldosteronism, Cushing's syndrome and adrenogenital syndrome, and nonfunctioning adrenocortical tumors. Weiss's criteria are a useful tool for histopathologically diagnosing adrenocortical carcinomas except for pediatric tumors and oncocytic tumors. Adrenomedullary tumors include pheochromocytoma, paraganglioma, and their malignant counterparts, which are known as components of some inherited tumor syndromes. The Shimada System predicts the prognosis of neuroblastic tumors. The adrenal gland is commonly involved by metastatic tumors. Merkel cell carcinoma and thymic neuroendocrine tumors are among the tumors of the diffuse neuroendocrine system many of which are to be described in each of the organ systems in this series of Atlas of Diagnostic Pathology. Ectopic hormone-producing tumors are one of the fascinating themes in pathology. Tumors may rarely heterotopically produce hypothalamus/pituitary hormones, calcitonin, parathyroid hormone-related protein, big insulin-like growth factor II, chorionic gonadotropin, erythropoietin, and so on. Finally inherited tumor syndromes are briefly described.
東京女子医科大学の論文