高感度アディポネクチン測定法の開発とその運動・栄養指導への応用

概要

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Adiponectin (AN) is secreted from adipose tissue and increases insulin sensitivity inboth the liver and skeletal muscle. A low level of AN in obese individuals is considered arisk factor for metabolic syndrome due to negative correlations of AN with body mass index(BMI) and visceral fat area (VFA). To determine levels of circulating AN, we developed ahighly sensitive immune complex transfer enzyme immunoassay (ICT-EIA) that useseasily collected dried blood on filter paper discs (DBD). The positive effects of exercise oncirculating AN levels have also been reported. And tea-catechin increases fatty acidoxidation in skeletal muscle and reduces the risk for metabolic syndrome. Thus, weinvestigated the use of AN as an index to evaluate the effects of exercise guidance and teacatechinintake for obese individuals.
徳島文理大学の論文