1105 マイクロチャンネル内壁に血管内皮細胞を播種する試み(S02-1 循環器系・呼吸器系の生体機能モデリング(1),S02 循環器系・呼吸器系の生体機能モデリング)

概要

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The technology of cell culture on a microchip is very important for regenerative medicine and biomechanics on the cell area. In this study, we are trying to disseminate normal human vascular endothelial cell (HUVEC) on the inner wall of microchannel for elucidation of the behavior of such cells in the blood flow. We fabricated a microchannel having a branch of 100μm in width on a quartz plate using a femtosecond laser micro/nano fabrication system. At the bottom of the channel, the blocks were placed regularly as a scaffold for cell attachment and its growth. After HUVECs seeded on the glass coated with matrigel and poly-L-lysine, we cultured and observed them in the microchannel.
一般社団法人日本機械学会の論文
2007-09-07