639 喘息の模擬実験 : 二重壁を持つ気道モデルの座屈に関する生体外実験(G02-7 シミュレーション(2),G02 バイオエンジニアリング)

概要

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Bronchial asthma is a kind of chronic bronchitis. It causes an airway narrowing and so makes breathing difficult. It is important to clarify its mechanism. The characteristic of asthmatic airway is that its bucked cross-section consists of many folds in the airway lumen. It is considered to be caused by a rapid constriction of smooth muscle. We paid attention to a rapid change in the transmural pressure as a model of the constriction of smooth muscle. In this study, to clarify the mechanism of the buckling, we used two-layered collapsible tubes as a model of the airway and used a shock tube which gave a sudden decrease in the pressure inside the collapsible tube. The cross-sectional shape of the tube was visualized by a laser sheet method and its behavior during the buckling was photographed by using a high speed video camera. We examined the influence of wall structure and Young's modules of the tube on buckling behavior.
一般社団法人日本機械学会の論文
2006-09-15