Identification of Novel Derivative of Helvolic Acid from Metarhizium anisopliae Grown in Medium with Insect Component(BIOCHEMICAL ENGINEERING)

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概要

• 論文の詳細を見る

• Entomopathogenic fungi are unique owing to their versatile ability to produce many bioactive compounds and from the dependence of their morphological differentiation on the presence of insect-derived materials. An entomopathogenic fungus, Metarhizium anisopliae HF293, was found to show insect-material-dependent production of antibacterial compounds, which were purified to homogeneity from 10-d culture broth when the production reached maximum. Two compounds were isolated: the major compound was determined to be helvolic acid and the minor one was a novel derivative of helvolic acid(1,2-dihydrohelvolic acid). Discovery of a novel bioactive com-pound indicated that insect-derived material would be a useful factor for enhancing the diversity of compounds produced by entomopathogenic fungi.

• 2008-05-25

著者

• IHARA Fumio

  Apple Research Station, National Institute of Fruit Tree Science

• Lee Si-young

  International Center For Biotechnology Osaka University

• Nihira Takuya

  International Center for Biotechnology, Osaka University

• Ihara Fumio

  Department Of Plant Protection National Institute Of Fruit Tree Science

• Ihara Fumio

  Apple Pest Control Research Subteam National Institute Of Fruit Tree Science

• IGARASHI Yasuhiro

  Biotechnology Research Center, Toyama Prefectural University

• Nihira T

  Osaka Univ. Osaka Jpn

• Nihira Takuya

  International Center For Biotechnology Osaka University

• Kinoshita Hiroshi

  International Center for Biotechnology, Osaka University

• Igarashi Yasuhiro

  Biotechnology Research Center Toyama Pref. Univ.

• Kinoshita Hiroshi

  Icbiotech Osaka Univ.

• Kinoshita Hiroshi

  International Center For Biotechnology Osaka University

• Nihira Takuya

  International Center For Biotechnology Osaka Univ.

• Igarashi Y

  Biotechnology Research Center Toyama Prefectural University

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