Studies on the Constituents of Orchidaceous Plants. VII. The C-24 Stereochemistry of Cyclohomonervilol and 24-Isopropenylcholesterol, Non-conventional Side Chain Triterpene and Sterol, from Nervilia purpurea SCHLECHTER(Organic,Chemical)
スポンサーリンク
概要
- 論文の詳細を見る
The C-24 stereochemistry of cyclohomonervilol, a non-conventional side chain triterpene isolated from Nervilia purpurea, was determined to be 24S by chemical transformation to 24S-dihydrocyelofuntumienol. Separation of a 24-epimeric mixture of chemically synthesized 24-isopropenylcholesterol was effectively achieved by reversed-phase high-performance liquid chromatography (HPLC), and the C-24 stereochemistry of each epimer was determined on the basis of chemical correlation with sitosterol or clionasterol. Then, 24ζ-isopropenylcholesterol, isolated from N. purpurea, was identified as 24S-isopropenylcholesterol by proton nuclear magnetic resonance and HPLC comparisons with the synthetic sampie.
- 公益社団法人日本薬学会の論文
- 1987-01-25
著者
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菊池 徹
Research Institute for WAKAN-YAKU (Oriental Medicines) Toyama Medical & Pharmaceutical University
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菊池 徹
富山医科薬科大学和漢薬研究所化学応用部門
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島 岳彦
Research Institute for Wakan-Yaku (Oriental Medicines), Toyama Medical and Pharmaceutical University
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島 岳彦
Research Institute For Wakan-yaku (oriental Medicines) Toyama Medical And Pharmaceutical University
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門田 重利
Research Institute For Wakan-yaku (oriental Medicines) Toyama Medical And Pharmaceutical University
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