Studies on the Constituents of Veratrum Plants. I. : Constituents of Veratrum maackii REG.; Isolation and Structure Determinatin of a New Alkaloid, Maackinine

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概要

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• The constituents of the roots and rhizoma of Veratrum maackii REG. (Liliaceae), wich are used as a Chinese crude drug "Li-lu, " were examined and a new steroidal alkaloid named maackinine was isolated along with five known alkaloids, germanitrine, verazine, angeloylzygadenine, zygadenine, and verazinin. The structure of maackinine was determined by the use of two-dimensional nuclear magnetic resonance (2-D NMR) techniques (fl-decoupled ^1H-^1H chemical shift correlation spectroscoy (COSY), ^1H-^1H COSY, ^1H-^<13>C COSY, and long-range ^1H-^<13>C COSY spectra). Assignments of ^1H- and ^<13>C-NMR signals of these steroidal alkaloids were also performed.

• 公益社団法人日本薬学会の論文
• 1989-11-25

著者

• 趙 偉傑

  医薬科学研究所

• 手塚 康弘

  Research Institute for WAKAN-YAKU (Oriental Medicines), Toyama Medical & Pharmaceutical University

• 菊池 徹

  Research Institute for WAKAN-YAKU (Oriental Medicines) Toyama Medical & Pharmaceutical University

• 菊池 徹

  富山医科薬科大学和漢薬研究所化学応用部門

• 菊池 徹

  Research Institute For Wakan-yaku (oriental Medicines) Toyama Medical And Pharmaceutical University

• 陳 益均

  Research Institute For Medical And Pharmaceutical Science Dalian

• 菊池 徹

  富山医薬大和漢薬研化学応用

• 趙 偉傑

  Research Institute for Wakan-Yaku (Oriental Medicines), Toyama Medical and Pharmaceutical University

• 郭 永沺

  Research Institute for Medical and Pharmaceutical Science, Dalian

• 郭 永沺

  Research Institute For Medical And Pharmaceutical Science Dalian

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