月盲症馬の臨床観察について
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概要
- 論文の詳細を見る
At Present the cause of periodic ophthalmia is unknown, excepting that there is a close relationship between periodic ophthalmia and leptospirosis. The onset of the attack of the disease is sudden, usually being noticed after the acute symptoms of the eye have already appeared. Therefore, it seemed that it is very difficult to expect the time of onset. During the period from March 1954 to Dec. 1955 the author made continuous observations of the general symptoms as well as the eye lesions of the experimental horse suffering from periodic ophthalmia. In this experiment the author observed that a definite change of temperature and pulsation always occurred in several days before the onset of the attack. It became possible to presume the time of the coming attack in near future, and to make a detailed observation from the beginning of attack to the severe stage of the disease. General symptoms which are depression or dullness and anorexia, bespeaking general disorder, lasted during the period of a attack, and the marked change of temperature and pulsation are observed during and sometimes till after the attack. In spite of the numbers of attacks, the advance of the eye disease is very slow, and it stays long in its early stage. In the eye lesions, iridocyclitis may have occurred at the beginning of, or sometimes before the attacks, followed by conjunctivitis or keratitis. It appeared that severity of photophobia, lacrimation etc. mainly depend upon the grade of the symptom of conjunctivitis or keratitis. From the result of this investigation the author believed that the typical attacks are from not only one simple causative agent but also the various factors-for instance, allergy of conjunctiva, outside irritants etc. Hematological researches revealed a moderate leucocytosis i.e. neutrophilia and eosinophilia, at the time of attacks. Aqueous humor and urine are taken very often for the examination of their physical condition. And repeated attempts both to demonstrate leptospirosis by dark-field examination and to culture in Kortohoff mediums what was taken from urine and aqueous humor, showed entirely negative results.
- 鹿児島大学の論文
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