Hormone and Immune Response, with Special Reference to Steroid Hormone 1. A Short Review
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概要
- 論文の詳細を見る
Substantial evidence has been accumulated to support the gonadal regulation of immune functions. They are mainly based on the following observations: i) the existence of sexual dimorphism in immune response, ii) alteration of immune response by gonadectomy or sex steroid replacement, iii) alteration of immune response during pregnancy, and iv) existence of sex steroid receptors in the thymus tissue which affect T cell function through thymic hormones produced in the gland. In the present study, we have tried to review some of this evidence by adding our own findings. We also referred to the experimental findings which show that the thymus, brain and gonads are close-related functionally, and form a functional axis, the so-called "hypothalamic-pituitary-gonadal-thymic" axis which is of great importance not only because it regulates immune response, but because its influence may extend to other organ system within the living body.
- 1990-03-08
著者
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SAKABE KOU
Department of Public Health and Molecular Toxicology, Kitasato University School of Pharmaceutical S
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Sakabe Kou
Department Of Anatomy School Of Medicine
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Sakabe Kou
Department Of Human Structure And Function Tokai University School Of Medicine
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Sakabe Kou
Department Of Anatomy And Cellular Biology Tokai University School Of Medicine
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SEIKI Kanji
Department of Anatomy, School of Medicine, Tokai University
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FUJII-HANAMOTO Hideko
Department of Anatomy, School of Medicine, Tokai University
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KAWASHIMA Issei
Department of Anatomy, School of Medicine, Tokai University
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Seiki Kanji
Department Of Anatomy School Of Medicine
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Seiki Kanji
Department Of Analomy School Of Medicine Tokai University
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Kawashima Issei
Department Of Anatomy School Of Medicine
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Sakabe K
Department Of Human Structure And Function Tokai University School Of Medicine
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Fujii-hanamoto Hideko
Department Of Anatomy School Of Medicine
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