An experimental study on the features of peri-implant epithelium: immunohistochemical and electron-microscopic observations
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概要
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The purpose of this study was to investigate the immunohistochemical and the ultrastructural features of the implant circumference epithelium of the beagle dog using various types of antibodies. The peri-implant epithelium was at an acute-angle from the gingival epithelium and was arranged in parallel to the implant surface. With immunohistochemical staining, the peri-implant epithelium was strongly positive for KL-1, and weakly positive for CK4, CK8 and CK19. These positive reactions for keratins and also for PCNA and BM-1 were similar to those seen in the oral mucosa. In the periimplant epithelium, a plentitude of microvilli were observed at the periphery of cells at the implant sites, and bacteria were observed between the implant and the peri-implant epithelium without the formation of half desmosomes. There were many lipid-like vacuoles or lysosome-like granules. The intercellular space was wider than the junctional epithelium, and random migrations of large numbers of neutrophils could be seen. Taken together, the peri-implant epithelium is similar to that seen in the oral mucosa, and it is structurally different from the junctional epithelium.
- 東京歯科大学の論文
著者
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Saitoh M
Department Of Dental Science Institute Of Personalized Medical Science Health Sciences University Of
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SHIMONO Masaki
Oral Health Science Center HRC7, Tokyo Dental College
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INOUE Takashi
Oral Health Science Center, Tokyo Dental College
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MATSUZAKA KENICHI
Oral Health Science Center, Department of Clinical Pathophysiology, Tokyo Dental College
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YOSHINARI MASAO
Oral Health Science Center, Department of Dental Material Science, Tokyo Dental College
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FUJISEKI MASATSUGU
Oral Health Science Center, Department of Pathology, Tokyo Dental College
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Saitoh Masato
Department Of Dental Science Institute Of Personalized Medical Science Health Sciences University Of
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Inoue T
Department Of Pathophysiology Tokyo Dental College
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Shimono Masaki
Oral Health Science Center Department Of Pathology Tokyo Dental College
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Shimono M
Oral Health Science Center Hrc7 Tokyo Dental College
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Shimono Masaki
Pathology Tokyo Dental College
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Yoshinari Masao
Oral Health Science Center Hrc7 Tokyo Dental College:department Of Dental Materials Science Tokyo De
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Yoshinari Masao
Department Of Dental Materials Science And Oral Health Science Center Tokyo Dental College
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Matsuzaka Kenichi
Oral Health Science Center Hrc7 Tokyo Dental College:department Of Clinical Pathophysiology Tokyo De
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Yoshinari M
Department Of Dental Materials Science And Oral Health Science Center Tokyo Dental College
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Fujiseki Masatsugu
Oral Health Science Center Department Of Pathology Tokyo Dental College
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Matsuzaka K
Oral Health Science Center Hrc7 Tokyo Dental College:department Of Clinical Pathophysiology Tokyo De
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Yoshinari M
Oral Health Science Center Hrc7 Tokyo Dental College:department Of Dental Materials Science Tokyo De
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Matsuzaka Kenichi
Oral Health Science Center Hrc7 Tokyo Dental College
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Yoshinari M
Oral Health Science Center Tokyo Dental College
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Inoue T
Oral Health Science Center Tokyo Dental College
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Fujiseki M
Oral Health Science Center, Department of Pathology, Tokyo Dental College
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