猫汎白血球減少症に関する研究 : II. ウイルスの各種抗原性

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Infectivity, hemagglutination (HA) activity and complement-fixation (CF) activity of feline parvovirus (FPV) were investigated with 11 strains of the virus. The peaks of infectivity, HA activity and CF activity were observed similarly at a buoyant density of 1.32-1.35 g/ml in CsCl gradient. The eleven strains of FPV had the same CF antigenicity and were not distinguished from one another. Both infectivity and HA activity were affected with potassium periodate (KIO_4) and formaldehyde. Since a receptor for viral hemagglutinin on the porcine erythrocyte was inactivated almost completely by trypsin, KIO_4 and α-amylase, and to some extent by formaldehyde, it was supposed to have the same character as a glycoprotein. The agglutinability of erythrocytes by the virus was reduced when treated with neuraminidase as well.
社団法人日本獣医学会の論文
1978-08-25