RABBIT LIVER ENZYMES RESPONSIBLE FOR REDUCTION OF NITROPOLYCYCLIC AROMATIC HYDROCARBONS
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概要
- 論文の詳細を見る
The present paper is the first description of mammalian nitroreductases acting upon nitropolycyclic aromatic hydrocarbons. Rabbit liver microsomal and cytosolic fractions have ability to reduce 1-nitropyrene or 2-nitrofluorene to the corresponding amine under anaerobic conditions. The nitroreductase activity in the former fraction is mainly due to a cytochrome P-450 system and that in the latter fraction is due to aldehyde oxidase.
- 公益社団法人日本薬学会の論文
- 1983-02-25
著者
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林 美鈴
Institute Of Pharmaceutical Sciences Hiroshima University School Of Medicine
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辰巳 淳
Institute of Pharmaceutical Sciences, Faculty of Medicine, Kyushu University
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辰巳 淳
広島大・医・薬
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辰巳 淳
Institute Of Pharmaceutical Sciences Hiroshima University School Of Medicine
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北村 繁幸
広島大・医・薬
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北村 繁幸
Institute of Pharmaceutical Sciences, Hiroshima University School of Medicine
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奈良井 紀子
Institute of Pharmaceutical Sciences, Hiroshima University, School of Medicine
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奈良井 紀子
Institute Of Pharmaceutical Sciences Hiroshima University School Of Medicine
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北村 繁幸
Institute Of Pharmaceutical Sciences Hiroshima University School Of Medicine
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