Metabolism of Furazolidone in Eels
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概要
- 論文の詳細を見る
The metabolism of an antibacterial nitrofuran, furazolidone (N-(5-nitro-2-furfurylidene)-3-amino-2-oxazolidone), was investigated in eels. When eels were bathed in a solution of the nitrofuran, ethyl acetate-extractable metabolites and polar, water-soluble metabolite (s) were formed from the nitrofuran. One of the former metabolites was isolated from the bathing solution and unequivocally identified as 3-(4-cyano-2-oxobutylideneamino)-2-oxazolidone by comparison with an authentic sample. This metabolite was also formed from the nitrofuran by an eel liver homogenate-catalyzed reaction.
- 公益社団法人日本薬学会の論文
- 1984-10-25
著者
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辰巳 淳
Institute of Pharmaceutical Sciences, Faculty of Medicine, Kyushu University
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辰巳 淳
Institute Of Pharmaceutical Sciences Hiroshima University School Of Medicine
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中別府 仁
Institute of Pharmaceutical Sciences, Hiroshima University School of Medicine
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中別府 仁
Institute Of Pharmaceutical Sciences Hiroshima University School Of Medicine
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