Estimation of Stress Distribution in the Convex Type Tablet using Specific Enzyme Activity as a Parameter

概要

論文の詳細を見る
The concentration and the distribution of stress by compression with several different pressures in convex type tablets were studied, measuring specific enzyme activities of proteinase as a parameter. As for the parts where stress center, a new zone which gives worse damages to the enzyme activity was found that appeared about two third from the center of tablets in the longitudinal direction. And the new zone was related to structural breakings in the experiment of compression of large two dimensional model. It was estimated that Lamination is closely related to the recovery of elastic deformation at the new zone and that Capping is related to that at upper corners. The new zone was proposed by authors to be called the L zone for its close relation to the phenomenon of Lamination.
社団法人日本薬学会の論文
1973-10-25