ヒヨコによるジギタリスの効力検定法
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概要
- 論文の詳細を見る
Experiments were made so as to examine the availability of young chicks for the assay of digitalis glycosides. Alar or jugular vein was cannulated and a volume of the test solution (Digitamin Injection, Shionogi) equivalent to 2 ml/kg was infused within a few sec. The dose was repeated at 5 min intervals until cardiac arrest was noticed. Problems of susceptibility difference depending on strain, sex, age, and feeding were examined. Influences of these factors on the susceptibility were not serious in practice. The order of susceptibility of tested animals was as follows : pigeon>chick>rat, mouse. From these results it is concluded that young chicks are available for digitalis assay if a sufficient number of animals is used.
- 公益社団法人日本薬学会の論文
- 1969-06-25
著者
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渡辺 和夫
Research Institute for Wakan-Yaku (Oriental Medicines), Toyama Medical and Pharmaceutical University
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福田 英臣
Faculty Of Pharmaceutical Sciences Nagoya City University
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渡辺 和夫
Faculty Of Pharmaceutical Sciences Nagoya City University:(present Address)faculty Of Pharmaceutical
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福田 英臣
名古屋市立大学薬学部
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渡辺 和夫
名古屋市立大学薬学部
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工藤 富貴子
名古屋市立大学薬学部
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渡辺 和夫
Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Nagoya City University
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