Some Pharmacological Factors involved in Formation and Prevention of Stress Ulcer in Rats
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概要
- 論文の詳細を見る
The pharmacological factors which affect the stress ulcer formation were studied in rats Some gastric functions, mainly gastric motility, secretion, blood circulation and protective action of gastric mucosa play the important roles in the ulcer formation induced by the stress which was inflicted by immobilization and immersing in water. Effect of some pharmacedynamic agents on the stress ulcer was examined, and it was found that the secretagogue action is more important than the other pharmacodynamic action tested. Effects of anticholinergics on the gastric functions were also studied, and the close relations between antiulcerous effect and depressive activity of gastric secretion and motility was confirmed. The protective action of gastric mucosa against gastric juice was estimated and the effect of stress and atropine on it was examined. Atropine seemed to have the effect inhibiting the decrease of the protective action of gastric mucosa.
- 公益社団法人日本薬学会の論文
- 1966-02-25
著者
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渡辺 和夫
Research Institute for Wakan-Yaku (Oriental Medicines), Toyama Medical and Pharmaceutical University
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渡辺 和夫
Faculty Of Pharmaceutical Sciences Nagoya City University:(present Address)faculty Of Pharmaceutical
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渡辺 和夫
Research Institute For Wakan-yaku (oriental Medicines) Toyama Medical And Pharmaceutical University
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渡辺 和夫
Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Nagoya City University
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