Parasite Mitochondria as a Target for Chemotherapy
スポンサーリンク
概要
- 論文の詳細を見る
The survival of parasites is dependent on that of the host. It is considered that parasites originated from nonparasitic ancestors and adapted to the environment in the host during the evolutional process, and developed hostand organ-specificities. Regarding energy metabolism, which is an essential factor for the survival, parasites adapt to the environment under a low oxygen tension in the host using metabolic systems which are very different from that of the host mammals. In such systems, parasite mitochondria play diverse roles. Especially, marked changes in the morphology and components of the mitochondria in the life cycle are very interesting in biological aspects such as developmental control and environmental adaptation. Such unique properties of parasite mitochondria could be promising targets for chemotherapy.
- 公益社団法人日本薬学会の論文
- 2001-06-01
著者
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Hayashi M
The Kitasaro Institute And School Of Pharmaceutical Sciences The Kitasato University
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Komiyama K
The Kitasaro Institute And School Of Pharmaceutical Sciences The Kitasato University
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Komiyama Kanki
The Kitasaro Institute And School Of Pharmaceutical Sciences The Kitasato University
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Kamei Kiseko
Department Of Phraseology Teikyo University School Of Medicine
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KITA Kiyoshi
Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo
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Hayashi Mitsuo
Institute For Life Science Research Asahi Chemical Industry Co. Ltd.
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Miyoshi Hideto
Kyoto Univ. Kyoto Jpn
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Miyoshi H
Gakushuin Univ. Tokyo Jpn
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Miyoshi H
Kyoto Univ. Kyoto
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Kita Kiyoshi
Department Of Biomedical Chemistry Graduate School Of Medicine The University Of Tokyo
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Kita K
Department Of Biomedical Chemistry Graduate School Of Medicine The University Of Tokyo
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MIYADERA Hiroko
Department of Biomedical Chemistry, Graduate School of Medicine, University of Tokyo
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Saruta Fumiko
Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo
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Miyoshi Hideto
Japan and Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University
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Hayashi Masahiko
Kitasato Institute For Life Sciences Kitasato University And The Kitasato Institute
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Saruta Fumiko
Department Of Biomedical Chemistry Graduate School Of Medicine The University Of Tokyo
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Miyadera H
Department Of Biomedical Chemistry Graduate School Of Medicine The University Of Tokyo
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