New Constituents from the Leaves of Morinda citrifolia
スポンサーリンク
概要
- 論文の詳細を見る
A new iridoid glycoside, citrifoside (1), and a new anthraquinone, 1,5,15-trimethylmorindol (2), together with 24 known compounds, were isolated from the leaves of Morinda citrifolia. The structures of the new compounds were elucidated by spectral data. 1,5,15-Trimethylmorindol (2) did not show significant cytotoxic activity by itself but showed cytotoxicity when combined with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), while citrifoside (1) did not show any activity even with TRAIL.
- 公益社団法人日本薬学会の論文
- 2007-02-01
著者
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Komiyama K
The Kitasaro Institute And School Of Pharmaceutical Sciences The Kitasato University
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HAYASHI Masahiko
The Kitasato Institute
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KOMIYAMA Kanki
The Kitasato Institute
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Komiyama Kanki
The Kitasaro Institute And School Of Pharmaceutical Sciences The Kitasato University
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Kamei Kiseko
Department Of Phraseology Teikyo University School Of Medicine
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Ohsaki Ayumi
Institute Of Biomaterials & Bioengineering Tokyo Medical & Dental University
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Hayashi Masahiko
The Kitasato Inst.
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TAKASHIMA Junko
Pharmaceuticals Research Division, Mitsubishi Pharma Corporation
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IKEDA Yoshitaka
Pharmaceuticals Research Division, Mitsubishi Pharma Corporation
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KISHIDA Akio
Institute of Biomaterials & Bioengineering, Tokyo Medical & Dental University
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Takashima Junko
Pharmaceuticals Research Division Mitsubishi Pharma Corporation
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Kishida Akio
Institute Of Biomaterials & Bioengineering Tokyo Medical & Dental University
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Kamei K
The Kitasato Institute
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Ikeda Yoshitaka
Pharmaceuticals Research Division Mitsubishi Pharma Corporation
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