Clinical effect and safety of oolong tea "ogonkei" for seasonal allergic rhino-conjunctivitis caused by pollen

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概要

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• 1998年の全国調査によると季節性アレルギー性鼻炎の発症率は13-16%と高く,アレルギー性鼻炎に対する天然物を利用した代替療法が近年注目されている。烏龍茶「黄金桂」はラットのPCA反応で抑制効果を示したため,スギ花粉症患者による試験を行い安全性と有効性を評価した。スギ花粉症の諸症状を有する成人を対象に,1日摂取量の烏龍茶「黄金桂」を6週間連続して摂取する試験を実施したところ,問診,身体測定,血圧測定,血液検査および尿検査において特に問題となる異常所見は認められず,安全性が確認された。花粉症の極期時でもくしゃみ(p<0.05),鼻水(p<0.001),鼻詰まり(p<0.01),涙目(p<0.001)において有効性を確認することができた。また,抗アレルギー剤の使用量も減少した。以上のことから,日常的に烏龍茶「黄金桂」を摂取することにより,スギ花粉時期における抗アレルギー剤の減量およびアレルギー症状の緩和に対し効果が期待できることが示唆された。

• 2008-02-29

著者

• 新納 仁

  (株)伊藤園中央研究所第三研究室

• OBARA Kengo

  (株)伊藤園中央研究所第三研究室

• SAGESAKA Yuko

  (株)伊藤園中央研究所第三研究室

• SUZUKI Megumi

  School of Medicine, Showa University

• IIGAYA Nanae

  Ogawa Otorhinolaryngology Clinic

• OGAWA Koji

  Ogawa Otorhinolaryngology Clinic

• HAYASHI Masahiko

  Kitasato Institute for Life Sciences, Katasato University

• CYONG Jong-Chol

  Nihon Pharmaceutical University

• Sagesaka Yuko

  伊藤園中央研究所 第三研究室

• Hayashi Masahiko

  Kitasato Institute For Life Sciences Kitasato University And The Kitasato Institute

• Suzuki Megumi

  School Of Medicine Showa University

• Hayashi Masahiko

  Kitasato Institute For Life Sciences Katasato University:(present Office)faculty Of Pharmacy Iwaki M

• Hayashi Masahiko

  Kitasato Institute For Life Science Kitasato University

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