Anti-aging Effect of DX-9386 in Senescence Accelerated Mouse
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概要
- 論文の詳細を見る
The effects of DX-9386,a traditional Chinese prescription (ginseng, acorus, polygala and hoelen) were studied on life span, the degree of senescence, motor activity and the antibody production response in senescence accelerated mouse (SAM). DX-9386-containing food was given to SAM for 13 consecutive months from 2 months of age. DX-9386 significantly prolonged the life span of SAM, prevented body weight decrease with aging and tended to improve the senile syndrome. The motor activity of SAMP8 was higher than that of SAMR1,and DX-9386 tended to increase the activity in SAMP8. The in vivo antibody production was markedly decreased in SAMP8 and DX-9386 showed no ameliorating effect on that. These results suggest that DX-9386 has anti-aging impact.
- 公益社団法人日本薬学会の論文
- 1994-06-15
著者
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齋藤 洋
Department Of Chemical Pharmacology Faculty Of Pharmaceutical Sciences The University Of Tokyo
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西山 信好
Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, The University of Tokyo
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西山 信好
Department Of Chemical Pharmacology Faculty Of Pharmaceutical Sciences The University Of Tokyo
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高科 謙
Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, The University of Tokyo
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張 永祥
Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, The University of Tokyo
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張 永祥
Department Of Chemical Pharmacology Faculty Of Pharmaceutical Sciences The University Of Tokyo
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Nishiyama Nobuyoshi
Department Of Chemical Pharmacology Faculty Of Pharmaceutical Sciences The University
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高科 謙
Department Of Chemical Pharmacology Faculty Of Pharmaceutical Sciences The University Of Tokyo
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