Effects of Crocus sativus L. on the Ethanol-Induced Impairment of Passive Avoidance Performances in Mice
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概要
- 論文の詳細を見る
The acute effects of an alcohol extract of Crocus sativus L. (CS-extract) were studied on learning and memory in step through (ST) and step down (SD) tests in normal as well as in learning-and memory-impaired mice. A single oral administration of CS-extract had no effects on memory registration, consolidation or retrieval in normal mice. CS-Extract reduced the ethanol-induced impairment of memory registration both in ST and SD tests and the ethanol-induced impairment of memory retrieval in SD test. CS-Extract decreased the motor activity (MA) and prolonged the sleeping time induced by hexobarbital. These results suggested that CS-extract ameliorates the impairment effects of ethanol on learning and memory processes, and possesses a sedative effect.
- 公益社団法人日本薬学会の論文
- 1994-02-15
著者
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齋藤 洋
Department Of Chemical Pharmacology Faculty Of Pharmaceutical Sciences The University Of Tokyo
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杉浦 実
Department Of Chemical Pharmacology Faculty Of Pharmaceutical Sciences The University Of Tokyo
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張 永祥
Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, The University of Tokyo
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正山 征洋
Department of Pharmacognosy, Faculty of Pharmaceutical Sciences, Kyushu University
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張 永祥
Department Of Chemical Pharmacology Faculty Of Pharmaceutical Sciences The University Of Tokyo
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正山 征洋
Department Of Pharmacognosy Faculty Of Pharmaceutical Sciences Kyushu University
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