Suppression of Hyperalgesia in Streptozotocin-Induced Diabetic Mice by a Lipopolysaccharide from Pantoea agglomerans
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概要
- 論文の詳細を見る
The ability of a lipopolysaccharide from Pantoea agglomerans (LPSp) to relieve hyperalgesia was examined by observing its inhibition of the decrease in the threshold for nociceptive perception, as determined by the tail-pinch test, in streptozotocin-induced diabetic mice. Subcutaneous injection of LPSp suppressed hyperalgesia in streptozotocin-induced diabetic mice and also exerted a therapeutic effect on hyperalgesia in these animals. The present data suggest that LPSp may be effective in relieving the pain associated with diabetic neuropathy.
- 社団法人日本薬学会の論文
- 1994-05-15
著者
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杣 源一郎
Biotechnology Research Center Teikyo University
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杣 源一郎
帝京大生物工学研究センター
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水野 伝一
Biotechnology Research Center, Teikyo University
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亀井 淳三
星薬大・薬物治療
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奥冨 隆文
Biotechnology Research Center Teikyo University
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奥富 隆文
Biotechnology Research Center Teikyo University
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水野 伝一
Biotechnology Research Center Teikyo University
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亀井 淳三
Department of Pharmacology, Faculty of Pharmaceutical Sciences, Hoshi University
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岩本 友理子
Department of Pharmacology, Faculty of Pharmaceutical Sciences, Hoshi University
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鈴木 勉
Department of Pharmacology, Faculty of Pharmaceutical Sciences, Hoshi University
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三澤 美和
Department of Pharmacology, Faculty of Pharmaceutical Sciences, Hoshi University
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粕谷 豊
Department of Pharmacology, Faculty of Pharmaceutical Sciences, Hoshi University
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粕谷 豊
Department Of Pharmacology Faculty Of Pharmaceutical Sciences Hoshi University
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奥富 隆文
帝京大学
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岩本 友理子
Department Of Pharmacology Faculty Of Pharmaceutical Sciences Hoshi University
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