BINDING ASSAY OF ALPHA-1 ADRENOCEPTOR SUBTYPES : RELATIONSHIP BETWEEN BIPHASIC SCATCHARD PLOT AND DISPLACEMENT CURVE
スポンサーリンク
概要
著者
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NAGATOMO Takafumi
Department of Pharmacology, Niigata University of Pharmacy and Applied Life Sciences
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Nagatomo Takafumi
Department Of Pharmacology Niigata College Of Pharmacy
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TSUCHIHASHI HIROSHI
Department of Surgery, Department of Medicine, Shiga University of Medical Science
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Nagatomo Takafumi
Department Of Pharmacology Faculty Of Pharmaceutical Sciences Niigata University Of Pharmacy And App
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Tsuchihashi Hiroshi
Department Of Pharmacology Niigata College Of Pharmacy
関連論文
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- Constitutively Active Mutant N111G of Angiotensin II Type 1 (AT_1) Receptor Induces Homologous Internalization Through Mediation of AT_1-Receptor Antagonist
- Assessment of Binding Affinity to 5-Hydroxytryptamine 2A (5-HT_) Receptor and Inverse Agonist Activity of Naftidrofuryl : Comparison With Those of Sarpogrelate
- Pharmacological Differences between Liu-Jun-Zi-Tang, a Traditional Chinese Herbal Medicine, and Domperidone on Isolated Guinea-Pig Ileum(Pharmacology)
- Actions of Liu-Jun-Zi-Tang, a Traditional Chinese Herbal Medicine, on Exogenous and Endogenous Opioid Systems in Isolated Guinea Pig Ileum
- Mutation of Important Amino Acid Residue of Asp104Lys in Human β_1-Adrenergic Receptor Triggers Functional and Constitutive Inactivation(Pharmacology)
- Identification of a Key Amino Acid of the Human 5-HT_ Serotonin Receptor Important for Sarpogrelate Binding
- Selectivity of Sarpogrelate to the Recombinant Human 5-HT_ Receptors as Assessed by Molecular Pharmacology and Molecular Modeling
- Inverse Agonist Activity of Sarpogrelate, a Selective 5-HT_-Receptor Antagonist, at the Constitutively Active Human 5-HT_ Receptor
- Assessment of Affinities and Dissociation Potencies of Several 5-HT_2 Antagonists to and from M_2 Muscarinic Receptor in Rat Heart Membranes(Pharmacology)
- Molecular modeling of the interaction of sarpogrelate and human 5-HT_, 5-HT_ and 5-HT_ receptor subtypes
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- Internalization of Constitutively Active N111G Mutant of AT1 Receptor Induced by Angiotensin II–Receptor Antagonists Candesartan, Losartan, and Telmisartan: Comparison With Valsartan
- Mutational Analysis of the α_-Adrenergic Receptor Binding Pocket of Antagonists by Radioligand Binding Assay(Pharmacology)
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- Identification of Amino Acid Residues Important for Sarpogrelate Binding to the Human 5-Hydroxytryptamine_ Serotonin Receptor
- Site-Directed Mutagenesis of the Serotonin 5-Hydroxytryptamine_ Receptor : Identification of Amino Acids Responsible for Sarpogrelate Binding(Pharmacology)
- Effects of Sarpogrelate, a Novel 5-HT_2 Antagonist, on 5-HT-Induced Endothelium-Dependent Relaxations in Porcine Coronary Artery
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- Molecular Characterization of Pharmacological Properties and Selectivity of SWR-0315NA for β_3-Adrenoceptors (Pharmacology)
- Structure-activity relationship studies of phenoxypropanolamine derivatives for β_3-adrenergic activity
- β-Adrenoceptors: Three-Dimensional Structures and Binding Sites for Ligands
- Inhibitory Effects of a Newly Synthesized 5-HT_2 Receptor Antagonist, AT-1015 (N-[2-[4-(5H-Dibenzo[a, d]cyclohepten-5-ylidene)piperidino]-ethyl]-1-formyl-4-piperidinecarboxamide Monohydrochloride Monohydrate), on Contraction and Relaxation of Pig Coronary
- Affinity for [^3H]Iloprost Binding Sites and cAMP Synthesis Activityof a 3-Oxa-methano Prostaglandin I_1Analog, SM-10906,in Human Platelets and Endothelial Cells
- Slow Dissociation of Long-Acting Ca^ Antagonist Amlodipine from ^3H-PN200-110 Binding Sites in Membranes of Rat Hearts and Brains
- cAMP-Independent Chloride Secretion Activated by a Vasoactive Intestinal Peptide in a Monolayer Culture of Human Bronchinal Epithelial Cells
- Hypertrophic Cardiomyopathy With Type I CD36 Deficiency
- Beta-blocking Potency and Selectivity of Bopindolol and Its Two Metabolites for β_1-and β_2-Adrenergic Receptors as Assessed by Radioligand Binding Assay
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- Binding Characteristics of ^I-Iodocyanopindolol to β-Adrenergic Receptors : Biphasic Scatchard Plts. II. : Effects of Selective Antagonists(Pharmacological)
- Edaravone Improves the Survival of Rats Subjected to Hemorrhagic Shock Without Resuscitation
- BINDING ASSAY OF ALPHA-1 ADRENOCEPTOR SUBTYPES : RELATIONSHIP BETWEEN BIPHASIC SCATCHARD PLOT AND DISPLACEMENT CURVE
- Alpha-blocking Potencies of Antihypertensive Agents (Prazosin, Terazosin, Bunazosin, SGB-1534 and Ketanserin) Having with Quinazoline or Quinazolinedione as Assessed by Radioligand Binding Assay Methods in Rat Brain
- BINDING CHARACTERISTICS OF 3H-DIHYDROALPRENOLOL TO β-ADRENOCEPTORS OF RAT HEART TREATED WITH NEURAMINIDASE
- Engineered Mutation of Some Important Amino Acids in Angiotensin II Type 1 (AT_1) Receptor Increases the Binding Affinity of AT_1-Receptor Antagonists
- Internalization of Constitutively Active N111G Mutant of AT_1 Receptor Induced by Angiotensin II-Receptor Antagonists Candesartan, Losartan, and Telmisartan : Comparison With Valsartan
- EFFECTS OF NEURAMINIDASE AND DEOXYRIBONUCLEASE ON THE β-ADRENERGIC RECEPTORS IN RAT HEART
- Effect of Site-directed Mutagenesis in Some Important Amino Acids of AT_1 Receptor on the Binding Affinity of the Agonist and Antagonists
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- Pharmacological and Molecular Studies for the Regulation of β_1-Adrenergic Receptors that Reveals Activation and Inactivation
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- Comparison of α1-Adrenoceptors between Rat Brain and Spleen
- Characteristics of 125I-lodocyanopindolol Binding to β-Adrenergic and Serotonin-1B Receptors of Rat Brain: Selectivity of β-Adrenergic Agents
- Mechanism of Inverse Agonist Action of Sarpogrelate at the Constitutively Active Mutant of Human 5-HT2A Receptor Revealed by Molecular Modeling
- Influence of polymeric effectors on binding of 3H-dihydroalprenolol to .BETA.-adrenergic receptor of rat brain.
- Beneficial effects of diltiazem on the ischemic derangements of the myocardial metabolism assessed by 31P-NMR in the isolated perfused rat heart.
- Binding characteristics of 3H-CGP12177 to .BETA.-adrenoceptors in rat myocardial membranes.
- Beta-Blockers Show Inverse Agonism to a Novel Constitutively Active Mutant of .BETA.1-Adrenoceptor
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- Effects of bunitrolol on adrenergic and serotonergic receptors.
- Binding characteristics of 3H-dihydroalprenolol to .BETA.-adrenergic receptors of rat brain: Influence of lectins.
- Beta-receptor blocking potencies of the three newly synthesized .BETA.-adrenergic antagonists (S-596,K-351,N-696) as assessed with the radioligand binding assay method in rat cardiac muscle membrane treated with neuraminidase.
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- Effects of deoxyribonuclease I and neuraminidase treatments on the specific binding of 3H-prazosin and 3H-quinuclidinyl benzilate (3H-QNB) to .ALPHA.-adrenergic and muscarinic receptors in rat myocardial membranes.
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- Alpha-1 Adrenoceptor Subtypes in Canine Aorta.