Pharmacological and Molecular Characterization of Novel SWR-Compounds for β-Adrenergic Receptors as assessed by Molecular Modeling, Site-Directed Mutagenesis, Binding Affinity and Functional Activity

スポンサーリンク

概要

• 論文の詳細を見る
• 2006-09-30

著者

• Nakamura Takashi

  Department of Cardiology, Saiseikai Shigaken Hospital

• HOSSAIN Murad

  Department of Pharmacology, Niigata University of Pharmacy and Applied Life Sciences

• NAGATOMO Takafumi

  Department of Pharmacology, Niigata University of Pharmacy and Applied Life Sciences

• 長友 孝文

  新潟薬科大学薬学部薬理学教室

• Ahmed Maruf

  Pharmacy Department University Of Rajshahi

• Ahmed Maruf

  バングラデシュ

• KOMIYAMA Tadazumi

  Department of Biochemistry, Niigata College of Pharmacy

• ISHIGURO Masaji

  Department of Chemical Biology, Faculty of Applied Life Sciences, Niigata University of Pharmacy and

• MUNTASIR Habib

  Department of Pharmacology, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and A

• Nagatomo T

  Dep. Of Pharmacology Fac. Of Pharmaceutical Sciences Niigata Univ. Of Pharmacy And Applied Life Scie

• MURAMATSU Ikunobu

  Division of Pharmacology, Department of Biochemistry and Bioinformative Sciences, School of Medicine

• AHMED Maruf

  Department of Pharmacology, Niigata University of Pharmacy and Applied Life Sciences

• Muramatsu Ikunobu

  Division Of Pharmacology Department Of Biochemistry And Bioinformative Sciences School Of Medicine U

• Muntasir Habib

  Department Of Pharmacology Faculty Of Pharmaceutical Sciences Niigata University Of Pharmacy And App

• Nagatomo Takafumi

  Department Of Pharmacology Faculty Of Pharmaceutical Sciences Niigata University Of Pharmacy And App

• Komiyama Tadazumi

  Department Of Biochemistry Faculty Of Pharmaceutical Sciences Niigata University Of Pharmacy And App

• Hossain Murad

  Department Of Pharmacology Faculty Of Pharmaceutical Sciences Niigata University Of Pharmacy And App

• Ishiguro Masaji

  Laboratory Of Chemical Biology Faculty Of Applied Life Sciences Niigata University Of Pharmacy And A

• Nakamura Takashi

  Department Of Cardiology Saiseikai Shiga Hospital

関連論文

• Erythropoietin Prevention Trial of Coronary Restenosis and Cardiac Remodeling After ST-Elevated Acute Myocardial Infarction (EPOC-AMI) : – A Pilot, Randomized, Placebo-Controlled Study –
• 1P113 Backbone NMR assignment and hydrogen exchange of goat α-lactalbumin(3. Protein folding and misfolding (1),Poster Session,Abstract,Meeting Program of EABS & BSJ 2006)
• 1P101 The role of Ca^ in the folding of goat α-Lactalbumin(3. Protein folding and misfolding (I),Poster Session,Abstract,Meeting Program of EABS & BSJ 2006)
• Engineered Mutation of Some Important Amino Acids in Angiotensin II Type 1 (AT1) Receptor Increases the Binding Affinity of AT1-Receptor Antagonists
• Constitutively Active Mutant N111G of Angiotensin II Type 1 (AT_1) Receptor Induces Homologous Internalization Through Mediation of AT_1-Receptor Antagonist
• Coulomb Excitation of ^24Si
• Coulomb Dissociation of ^23Al
• Coulomb Excitation of ^Si
• Coulomb Dissociation of ^Al
• Assessment of Binding Affinity to 5-Hydroxytryptamine 2A (5-HT_) Receptor and Inverse Agonist Activity of Naftidrofuryl : Comparison With Those of Sarpogrelate
• Evaluation of a commercial PET tomograph-based system for the quantitative assessment of rCBF, rOEF and rCMRO_2 by using sequential administration of ^O-labeled compounds
• Identification of New Isotopes ^Pd and ^Pd Produced by In-Flight Fission of 345 MeV/nucleon ^U : First Results from the RIKEN RI Beam Factory(Nuclear physics)
• Inelastic Scattering of ^12Be with ^4He
• Inelastic Scattering of ^Be with ^4He
• Study of the ^7Be (p,γ)^8B Reaction with the Coulomb Dissociation Method
• The Design and Performance of Multiwire Proportional Chambers for High Flux Beam Monitoring
• Development of a New High-Speed Measuring System to Analyze the Dental Cast Form
• Long-term survivorship analysis of hip arthroplasty with vitallium mold cup
• Mutation of Important Amino Acid Residue of Asp104Lys in Human β_1-Adrenergic Receptor Triggers Functional and Constitutive Inactivation(Pharmacology)
• Identification of a Key Amino Acid of the Human 5-HT_ Serotonin Receptor Important for Sarpogrelate Binding
• Selectivity of Sarpogrelate to the Recombinant Human 5-HT_ Receptors as Assessed by Molecular Pharmacology and Molecular Modeling
• Non-Contact Evaluation for Articular Cartilage Using Ultrasound
• Calibration of a DBF Receiving Array Antenna by Using a Reference Sequence for Systems in Power-Limited Channels
• Prevalence of Coronary Artery Disease in Japanese Patients With Cerebral Infarction : Impact of Metabolic Syndrome and Intracranial Large Artery Atherosclerosis
• PJ-223 Behavioral Monitoring in Life-style Intervention Can Predict Cardiovascular Events Independently of Major Biological Risk Factors in High-risk Hypertensive Patients(Hypertension, clinical-9 (H) PJ38,Poster Session (Japanese),The 70th Anniversary An
• Severe erosive arthropathy requiring surgical treatments in systemic lupus erythematosus
• Development of General-Purpose Particle and Heavy Ion Transport Monte Carlo Code
• A Field-Theoretic Model of Macroscopic Quantum Nucleation
• MECHANISM OF CIRCULATORY COLLAPSE IN RATS WITH SPONTANEOUSLYOCCURING HYPERTRORHIC CARDIOMYOPATHY
• Peptic ulcer recurrence during maintenance therapy with H^2-receptor antagonist following first-line therapy with proton pump inhibitor
• Internalization of Constitutively Active N111G Mutant of AT1 Receptor Induced by Angiotensin II–Receptor Antagonists Candesartan, Losartan, and Telmisartan: Comparison With Valsartan
• Amino Acids of the Human α_-Adrenergic Receptor Involved in Antagonist Binding
• Pharmacological and Molecular Characterization of Novel SWR-Compounds for β-Adrenergic Receptors as assessed by Molecular Modeling, Site-Directed Mutagenesis, Binding Affinity and Functional Activity
• Assessment of Affinity and Dissociation Ability of a Newly Synthesized 5-HT_2 Antagonist, AT-1015: Comparison With Other 5-HT_2 Antagonists
• DPJ-050 Comprehensive Cardiac Rehabilitation Improves Clinical Outcome in Patients with Acute Coronary Syndrome after Implantation of Drug-eluting Stents(DPJ09,Exercise Test/Cardiac Rehabilitation (H),Digital Poster Session (Japanese),The 73rd Annual Scie
• PJ-117 Combination of Carotid Arterial Wall Thickness and Stiffness Parameters Improves Prediction of Target Organ Damage in Patients with Essential Hypertension(Hypertension, Clinical 2 (H) : PJ20)(Poster Session (Japanese))
• Validation of the Japanese version of the Roland-Morris Disability Questionnaire
• IMMUNOELECTRON MICROSCOPIC LOCALIZATION OF HUMAN T-CELL LEUKEMIA VIRUS TYPE-I ANTIGENS (Immuno-Histochemistry and Cytochemistry)
• Identification of a Key Amino Acid of the Human 5-HT2B Serotonin Receptor Important for Sarpogrelate Binding
• Isolated Left Ventricular Noncompaction Was not a Very Rare Disorder in an Adult Population
• Habitual Walking Improves Distensibility of Central Artery in Patients with Essential Hypertension : Relation to Blood Pressure Reduction and Energy Metabolism
• Energy Spectrum of Ultra High Energy γ-Rays from Supernova
• Time Variation of Ultra High Energy γ-Ray from SN1987A
• Response Function Measurements of the Self-TOF Neutron Detector for Neutrons up to 800 MeV
• The Recovery of the Walking Ability of Patients at Early Stages after Total Hip Arthroplasty from the Perspective of the Displacement of the Center of Gravity
• Neuroprotection and Enhanced Recovery With Edaravone After Acute Spinal Cord Injury in Rats
• Expression Profile of Amylolytic Genes in Aspergillus nidulans
• β-Adrenoceptors: Three-Dimensional Structures and Binding Sites for Ligands
• An Off-Axis Jet Model for GRB 980425 and Low Energy Gamma-Ray Bursts(Poster)
• Erythropoietin Prevention Trial of Coronary Restenosis and Cardiac Remodeling After ST-Elevated Acute Myocardial Infarction (EPOC-AMI) : A Pilot, Randomized, Placebo-Controlled Study
• Pharmacological Tests in 100 Patients with Intractable Pain
• Raw Materials for Low-Activation Concrete Neutron Shields
• Correlation between Tritium and ^Eu Induced in Various Types of Concrete by Thermal Neutron Irradiation
• Design and Implementation of a Community-based Limb Salvage Program for ESRD Patients
• Inhibitory Effects of a Newly Synthesized 5-HT_2 Receptor Antagonist, AT-1015 (N-[2-[4-(5H-Dibenzo[a, d]cyclohepten-5-ylidene)piperidino]-ethyl]-1-formyl-4-piperidinecarboxamide Monohydrochloride Monohydrate), on Contraction and Relaxation of Pig Coronary
• Comparative Analyses of Fatty Acid Compositions in Rice Grain Glycerolipids among Three Cultivars with Different Chilling Susceptibilities
• Preparation of and Immunoelectron Microscopy with a Monoclonal Antibody to the Structural Protein of a Retrovirus Produced in a Human Lymphoblastoid Cell Line
• Characterization of the Complex between α_2-Macroglobulin and a Serine Proteinase from Bacillus natto(Biological Chemistry)
• The Long-Term Effect of Eicosapentaenoic Acid on Serum Levels of Lipoprotein (a) and Lipids in Patients with Vascular Disease
• Interaction of π-Electrons in the Acetylene Molecule
• Cross-sectional analysis of the surface ceramic layer developed on Ti metal by NaOH-heat treatment and soaking in SBF
• Tackler's bony spur in sumo wrestlers : a report of two cases
• Gravitational Radiation from a Particle with Orbital Angular Momentum Plunging into a Kerr Black Hole : Astrophysics and Relativity
• General Relativistic Collapse to Black Holes and Gravitational Waves from Black Holes
• Gravitational Radiation from a Particle Scattered by a Kerr Black Hole : Astrophysics and Relativity
• X-Rays and γ-Rays from a Non-Spherical Patchy Supernova Ejecta : Astrophysics and Relativity
• O-C2 Angle as a Predictor of Dyspnea and/or Dysphagia After Occipitocervical Fusion
• Atlantoaxial Transarticular Screw Fixation With Posterior Wiring Using Polyethylene Cable : Facet Fusion Despite Posterior Graft Resorption in Rheumatoid Patients
• Vertebral Artery Injury During Cervical Spine Surgery : A Survey of More than 5600 Operations
• Pneumoretroperitoneum, Pneumomediastinum, Pneumopericardium, and Subcutaneous Emphysema Complicating Sigmoidoscopy : Report of a Case
• (重イオン慣性核融合の新しい展開)
• Natural course of desmoid-type fibromatosis
• Elevation of lipid peroxide level and production of hydroxy lipids in cultured Hepa-T1 cells by oxidative stressors
• Fracture Resistance of Inlay-retained Fixed Partial Dentures Reinforced with Fiberreinforced Composite
• In Vitro Study on Marginal and Internal Fit of CAD/CAM All-Ceramic Crowns
• Application of a Dental CAD/CAM System to the Production of All-ceramic Crowns
• Collective Instabilities of Self-Gravitating Systems. III : Disk-Halo System
• Collective Instabilities of Self-Gravitating Systems. II : Instabilities Due to Temperature Anisotropy
• Collective Instabilities of Self-Gravitating Systems : Infinite Homogeneous Case
• The Clinical Risk of Vertebral Artery Injury From Cervical Pedicle Screws Inserted in Degenerative Vertebrae
• Transpedicular Screw Placement Evaluated by Axial Computed Tomography of the Cervical Pedicle
• Atlantoaxial Transarticular Screw Fixation for a High-Riding Vertebral Artery
• Cervical disc herniation causing localized ipsilateral popliteal pain
• Pseudoaneurysm of the Deep Circumflex Iliac Artery : A Rare Complication at an Anterior Iliac Bone Graft Donor Site
• Sclerotherapy for Varicose Veins of the Lower Legs in Patients with Dysplasminogenemia
• Remarkable Stereochemical Features of Ene Reaction of 2-(Alkylthio)crotyl Silyl Ethers. Proposal of a Six-Membered Chair-like Transition State
• Hyaluronan inhibits IL-1β-stimulated collagenase production via down-regulation of phosphorylated p38 in SW-1353 human chondrosarcoma cells
• Lack of increase in postoperative complications with low-dose methotrexate therapy in patients with rheumatoid arthritis undergoing elective orthopedic surgery
• Requirement of mitogen-activated protein kinase for collagenase production by the fibronectin fragment in human articular chondrocytes in culture
• Metabolic balance of streams draining urban and agricultural watersheds in central Japan
• The Coagulofibrinolytic State of Patients with Primary Varicose Veins of the Lower Legs
• Electrophoretic Deposition Behavior of Ceria-stabilized Zirconia/Alumina Powder
• Synthesis and Characterization of Novel Phosphido-Bridged Bimetallic Complexes of Molybdenum and Tungsten
• Preparation of Monodispersed Cu Nanoparticles by Microwave-Assisted Alcohol Reduction
• A Null Test of the Cosmological Constant
• Apatite formation on surface titanate layer with different Na content on Ti metal
• Preparation of bioactive Ti and its alloys via electrochemical treatment in sulfuric acid solution
• Superior mesenteric arterial embolism : treatment by trans-catheter thrombo-aspiration
• Energy, Momentum and Angular Momentum of Gravitational Waves Induced by a Particle Plunging into a Schwarzschild Black Hole
• Gravitational Waves from a Particle Scattered by a Schwarzschild Black Hole : Astrophysics and Relativity

もっと見る 閉じる

スポンサーリンク