Regional Changes in Brain Noradrenergic Activity Elicited by a Decrease in Blood Pressure
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概要
- 論文の詳細を見る
Using high performance liquid chromatography with electrochemical detection, the level of 3-methoxy-4-hydroxyphenylethylene glycol (MHPG), an index of noradrenaline release, was determined in regions of the brainstem and hypothalamus of rats after acute hypotension induced by hydralazine. In hypotensive rats, an increase in MHPG concentrations was observed in the posterior hypothalamus, while no significant changes were seen for all the other regions. These results suggest that hypotension results in an enhancement of noradrenaline release in the posterior hypothalamus in rats.
- 公益社団法人日本薬学会の論文
著者
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Amano Hiro
Department Of Pharmacology Yokohama City University School Of Medicine:(present Address)division Of
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KUBO Takao
Department of Pharmacology, Showa College of Pharmaceutical Sciences
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Kubo T
Department Of Pharmacology Yokohama City University School Of Medicine
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Kubo Takao
Department Of Pharmacology Showa College Of Pharmaceutical Sciences
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MISU Yoshimi
Department of Pharmacology, Yokohama City University School of Medicine
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Kambe T
Department Of Pharmacology Showa Pharmaceutical University
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Misu Yoshimi
Department Of Pharmacology Yokohama City University School Of Medicine
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MISU Yoshimi
Department of Pharmacologv, faculty of Pharmaceutical Scieuces, Kyoto University
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