PROLONGATION OF LIFE SPAN OF DYSTROPHIC HAMSTER BY CYSTEINE PROTEINASE INHIBITOR, LOXISTATIN (EST)
スポンサーリンク
概要
- 論文の詳細を見る
We studied the effect of loxistation (EST), an orally applicable cysteine proteinase inhibitor, on dystrophic hamsters, UM-X7.1.E-64-c, an active form of EST, was continuously found in plasma when the feed containing EST was given ad libitum. The drug concentration in plasma of dystrophic hamsters receiving EST feed showed distinct dose dependency. A diet containing EST from weaning to death significantly prolonged the survival period of the dystrophic hamsters.
- 公益社団法人日本薬学会の論文
著者
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Kimura M
Health Science Center At San Antonio The University Of Texas
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HANADA Kazunori
Research Laboratories, Taisho Pharmaceutical Co., Ltd.
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Kimura M
Tsumura & Co. Ltd. Ibaraki Jpn
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Kimura Masayasu
Department Of Chemical Pharmacology Faculty Of Phrmaceutical Sciemes Toyama Medical And Pharmaceutic
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Omura Sadafumi
Research Center, Taisho Pharmaceutical Co., LTD.
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Tamai Masaharu
Research Center, Taisho Pharmaceutical Co., Ltd.
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Hanada Kazunori
Research Laboratories Taisho Pharmaceutical Co. Ltd.
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Hanada Kazunori
Research Center Taisho Pharmaceutical Co. Ltd.:national Center For Nervous Mental And Muscular Disor
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Hanada Kazunori
Medicinal Research Laboratories Taisho Pharmaceutical Co. Ltd.
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Hanada Kazunori
Research Center Taisho Pharmaceutical Co. Ltd.
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Hanada Kazunori
Medicinal Resesarch Laboratories Taisho Pharmaceutical Co. Ltd.
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Kimura M
Taisho Pharmaceutical Co. Ltd. Saitama Jpn
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KIMURA MASAAKI
Research Center, Taisho Pharmaceutical Co., Ltd.
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SUGITA HIDEO
Research Center, Taisho Pharmaceutical Co., Ltd.
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Sugita Hideo
Research Center Taisho Pharmaceutical Co. Ltd.:national Center For Nervous Mental And Muscular Disor
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Tamai M
Taisho Pharmaceutical Co. Ltd. Saitama Jpn
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Tamai Masaharu
Research Center Taisho Pharmaceutical Co. Ltd.
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Omura S
Taisho Pharmaceutical Co. Ltd. Saitama Jpn
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Omura Sadafumi
Research Center Taisho Pharmaceutical Co. Ltd.
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Kimura Masaaki
Research Center Taisho Pharmaceutical Co. Ltd.
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