New Strong Fibrates with Piperidine Moiety
スポンサーリンク
概要
- 論文の詳細を見る
New fibrates containing piperidine, 4-hydroxypiperidine, piperidin-3-ene, and piperazine moieties in the structures were synthesized and evaluated. Among the synthesized compounds, 2-[3-[1-(4-fluorobenzoyl)-piperidin-4yl]phenoxy]-2-methylpropanoic acid (9aA : AHL-157) showed very superior activities in decreasing triglyceride, cholesterol, and blood sugar compared to bezafibrate in mice and rats.
- 公益社団法人日本薬学会の論文
- 2000-12-01
著者
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佐藤 真悟
Faculty of Pharmaceutical Sciences, Kanazawa University
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Sato S
Tsitkuha Research Laboratories
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SAKAMOTO Takao
Graduate School of Pharmaceutical Sciences, Tohoku University
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Hasegawa S
Tohoku Pharmaceutical Univ. Sendai Jpn
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Hasegawa Susumu
Department Of Radiopharmacy Tohoku Pharmaceutical Uiniversity.
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Sato S
Hisamitsu Pharmaceutical Co. Ltd. Ibaraki Jpn
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Sakamoto Takao
Graduate School Of Pharmaceutical Sciences Tohoku University
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SATO Susumu
Central Research Labs., SS Pharmaceutical Co., Ltd.
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KOMOTO Teruo
Central Research Laboratories SSP Co., Ltd.
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Komoto Teruo
Central Research Laboratories Ssp Co. Ltd.:graduate School Of Pharmaceutical Sciences Tohoku Univers
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HIROTA Hiroyuki
Central Research Labs., SSP Co., Ltd.,
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OTSUKA Mari
Central Research Labs., SSP Co., Ltd.,
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KOTAKE Jiro
Central Research Labs., SSP Co., Ltd.,
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HASEGAWA Susumu
Central Research Labs., SSP Co., Ltd.,
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KOYA Hidehiko
Central Research Labs., SSP Co., Ltd.,
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Koya Hidehiko
Central Research Labs. Ssp Co. Ltd.
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Kotake Jiro
Central Research Labs. Ssp Co. Ltd.
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Kotake Jiro
Central Research Laboratories Ssp Co. Ltd.
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Hirota H
Central Research Labs. Ssp Co. Ltd.
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Otsuka Mari
Central Research Labs. Ssp Co. Ltd.
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Hirota Hiroyuki
Central Research Labs. Ssp Co. Ltd.
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