NOVEL AND REGIOSELECTIVE LITHIATION OF THE UNSYMMETRICAL HANTZSCH-TYPE 1,4-DIHYDROPYRIDINE BY PARTICIPATION OF THE NEIGHBORING SULFINYL GROUP

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概要

• 論文の詳細を見る

• The C-6 methyl group of methyl (4R, S_S)-2,4,6-trimethyl-5-(p-tolylsulfinyl)-1,4-dihydropyridine-3-carboxylate (2) was found to be regioselectively lithiated by participation of the neighboring sulfinyl group, giving rise to the 6-modified Hantzsch-type compounds by treatment with n-butyllihium and the electrophiles.

• 公益社団法人日本薬学会の論文
• 1996-02-15

著者

• 今西 武

  大阪大学大学院薬学研究科

• IMANISHI Takeshi

  Faculty of Pharmaceutical Sciences, Osaka University

• Imanishi Takeshi

  Graduate Shool Of Pharmaceutical Sciences Osaka University

• Imanishi Takeshi

  Faculty Of Pharmaceutical Sciences Osaka University

• Nishimoto Masahiro

  Faculty Of Pharmaceutical Sciences Osaka University

• 西本 昌弘

  Faculty Of Pharmaceutical Sciences Osaka University

• Obika Satoshi

  Faculty Of Pharmaceutical Sciences Osaka University

• MIYASHITA Kazuyuki

  Faculty of Pharmaceutical Sciences, Osaka University

• Imamura T

  Faculty Of Pharmaceutical Sciences Osaka University

• Nishimoto M

  Faculty Of Pharmaceutical Sciences Osaka University

• MIYASHITA Kazuyuki

  Graduate Shool of Pharmaceutical Sciences, Osaka University

• 小比賀 聡

  Osaka Univ. Osaka Jpn

• MURAFUJI Hidenobu

  Faculty of Pharmaceutical Sciences, Osaka University

• Miyashita K

  Graduate Shool Of Pharmaceutical Sciences Osaka University

• Miyashita Kazuyuki

  Faculty Of Pharmaceutical Sciences Osaka University

• Murafuji Hidenobu

  Faculty Of Pharmaceutical Sciences Osaka University

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