Arylnaphthalene Lignans as Novel Series of Hypolipidemic Agents Raising High-Density Lipoprotein Level
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概要
- 論文の詳細を見る
A series of arylnaphthalene lignans were synthesized and tested for hypolipidemic activity. The most potent compound (4b) (TA-7552) not only reduced serum cholesterol, but also increased high-density lipoproteins cholesterol in rats. The effective dose of 4b is 100 times less than that of cholestyramine. Structure-activity relationships are discussed.
- 社団法人日本薬学会の論文
- 1995-10-15
著者
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近藤 一彦
Research Laboratory of Applied Biochemistry, Tanabe Seiyaku Co., Ltd.,
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岩崎 為雄
Research Laboratory of Applied Biochemistry, Tanabe Seiyaku Co., Ltd.
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黒田 徹
Research Laboratories Of Tanabe Seiyaku Co. Ltd.
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近藤 一彦
Research Laboratories Of Tanabe Seiyaku Co. Ltd.
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西谷 喬
Research Laboratories of Tanabe Seiyaku Co., Ltd.,
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平社 和之
Research Laboratories of Tanabe Seiyaku Co., Ltd.,
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大谷 章雄
Research Laboratories of Tanabe Seiyaku Co., Ltd.,
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高島 紘毅
Research Laboratories of Tanabe Seiyaku Co., Ltd.,
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高島 紘毅
Research Laboratories Of Tanabe Seiyaku Co. Ltd.
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大谷 章雄
Research Laboratories Of Tanabe Seiyaku Co. Ltd.
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西谷 喬
Research Laboratories Of Tanabe Seiyaku Co. Ltd.
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平社 和之
Research Laboratories Of Tanabe Seiyaku Co. Ltd.
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岩崎 為雄
Research Laboratories Of Tanabe Seiyaku Co. Ltd.
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