Syntheses and Antiulcer Activities of 2-Aminonorbornene Derivatives
スポンサーリンク
概要
- 論文の詳細を見る
2,2,-Disubstituted norbornenes (1,2), 2,2-Disubstituted norbornane (3), 2,2,3-trisubstituted norbornenes (4,5), oxanorbornenes (6) and azanorbornenes (7) were synthesized by the Diels-Alder reaction using α, β-dehydroamino acids as a key step, and their antiulcer activities were examined. The oxazolidine derivative (1h) exhibited the most potent activities against several ulcer-models in rat.
- 社団法人日本薬学会の論文
- 1992-01-25
著者
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岩崎 為雄
Research Laboratory of Applied Biochemistry, Tanabe Seiyaku Co., Ltd.
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西谷 喬
Research Laboratories of Tanabe Seiyaku Co., Ltd.,
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山崎 裕義
Research Laboratory of Applied Biochemistry, Tanabe Seiyaku Co., Ltd.,
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堀川 袷志
田辺製薬・拓新研
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玉木 元
Biological Research Laboratory, Tanabe Seiyaku Co,. Ltd.
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堀川 裕志
Research Laboratory of Applied Biochemistry, Tanabe Seiyaku Co., Ltd.,
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野坂 邦雄
Biological Research Laboratory, Tanabe Seiyaku Co., Ltd.,
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西谷 喬
Research Laboratories Of Tanabe Seiyaku Co. Ltd.
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野坂 邦雄
Biological Research Laboratory Tanabe Seiyaku Co. Ltd.
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岩崎 為雄
Research Laboratories Of Tanabe Seiyaku Co. Ltd.
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Tamaki Hajime
Pharmacological Resarch Laboratory Tanabe Seiyaku Co. Ltd.
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Tamaki H
Pharmacological Research Laboratory Tanabe Seiyaku Co. Ltd.
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山崎 裕義
Research Laboratory Of Applied Biochemistry Tanabe Seiyaku Co. Ltd.
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