An Acidic Polysaccharide Having Activity on the Reticuloendothelial System from the Root of Astragalus mongholicus

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概要

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• An acidic polysaccharide, designated as AMon-S, was isolated from the roots of Astragalus mongholicus BUNGE. It was homogeneous on electrophoresis and gel chromatography, and its molecular mass was estimated to be 7.6×10^4. It showed significant reticuloendothelial system-potentiating activity in a carbon clearance test. It is composed of L-arabinose : D-galactose : D-galacturonic acid : D-glucuronic acid in the molar ratio of 18 : 18 : 1 : 1,in addition to small amounts of O-adetyl groups and peptide moiety. A part of the hexuronic acid residues exist as the methyl esters. Methylation analysis, carbon-13 nuclear magnetic resonance and periodate oxidation studies enabled elucidation of its structural features and revealed mainly α-arabino-β-3,6-galactan type structural units.

• 1991-11-25

著者

• 清水 訓子

  Kyoritsu College Of Pharmacy

• 友田 正司

  Kyoritsu College of Pharmacy

• 権田 良子

  Kyoritsu College of Pharmacy

• 金成 美枝子

  Kyoritsu College of Pharmacy

• 金成 美枝子

  Kyoritsu College Of Pharmacy Shibakoen

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