Characterization of Two Polysaccharides Having Activity on the Reticuloendothelial System from the Root of Glycyrrhiza uralensis

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概要

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• Two polysaccharides, called glycyrrhizans UA and UB, were isolated from the root of Glycyrrhiza uralensis FISCHER. They were homogeneous on electrophoresis and gel chromatography, and showed reticuloendothelial system-potentiating activity in a carbon clearance test. Glycyrrhizan UA is composed of L-arabinose : D-galactose : L-rhamnose : D-galacturonic acid in the molar ratio of 20 : 14 : 1 : 3,and glycyrrhizan UB is composed of L-arabinose : D-galactose : D-glucose : L-rhamnose : D-galacturonic acid in the molar ratio of 12 : 10 : 1 : 10 : 20,in addition to small amounts of O-acetyl groups and peptide moiety, respectively. About 10% (glycyrrhizan UA) and 35% (glycyrrhizan UB) of the D-galacturonic acid residues exist as the methyl esters. Methylation analysis, carbon-13 nuclear magnetic resonance and periodate oxidation studies indicated their structural features.

• 1990-06-25

著者

• 清水 訓子

  Kyoritsu College Of Pharmacy

• 友田 正司

  Kyoritsu College of Pharmacy

• 権田 良子

  Kyoritsu College of Pharmacy

• 金成 美枝子

  Kyoritsu College of Pharmacy

• 奥田 有子

  Kyoritsu College Of Pharmacy

• 新井 澄子

  Kyoritsu College of Pharmacy

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