A ^<19> F NMR STUDY OF 2-DEOXY-2-FLUORO-D-GALACTOSE IN MICE

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概要

• 論文の詳細を見る

• The metabolic pathway of 2-deoxy-2-fluoro-D-galactose (FDGal) in mice was studied by ^<19>F NMR. Efficient accumulation of FDGal in liver was demonstrated by NMR, which is consistent with the results of Ishiwata et al. using radioactive ^<18>FDGal.The new discovery is that this fluorinated hexose was converted to 2-deoxy-2-fluoro-D-glucose (FDG) through UDP-FDGal and UDP-FDG apparently by the action of UDP-Gal epimerase.

• 公益社団法人日本薬学会の論文
• 1988-10-25

著者

• 小嶋 正治

  Faculty Of Pharmaceutical Sciences Kyusyu University

• 金沢 洋子

  Faculty of Pharmaceutical Sciences, Kyushu University

• 原田平 輝志

  Faculty of Pharmaceutical Sciences, Kyushu University

• 原田平 輝志

  Faculty Of Pharmaceutical Sciences Kyusyu University

• 栗林 悟

  Faculty of Pharmaceutical Sciences, Kyusyu University

• 金沢 洋子

  Faculty Of Pharmaceutical Sciences Kyushu University

• 小嶋 正治

  Faculty Of Pharmaceutical Sciences Kyushu University

• 栗林 悟

  Faculty Of Pharmaceutical Sciences Kyusyu University

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