Metabolism of Budralazine, a New Antihypertensive Agent. II. Metabolic Pathways of Budralazine in Rats
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概要
- 論文の詳細を見る
The metabolic pathways of budralazine were studied in vivo and in vitro experiments and characterized as follows ; 1) 3-methyl-s-triazolo [3,4-a] phthalazine (M-1), one of the major metabolites of budralazine, was mainly biotransformed via 1-hydrazinophthalazine. 2) s-triazolo [3,4-a] phthalazine (M-3) was also biotransformed via 1-hydrazinophthalazine. 3) Experiments using liver preparations of rat were also discussed briefly.
- 公益社団法人日本薬学会の論文
- 1977-04-25
著者
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諸井 黎明
Research Institute, Daiichi Seiyaku Co., Ltd.
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秋元 健
Research Institute Daiichi Seiyaku Co. Ltd.
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小野 健司
Research Institute, Daiichi Seiyaku Co., Ltd.
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斎藤 董
Research Institute, Daiichi Seiyaku Co., Ltd.
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佐野 光司
Research Institute, Daiichi Seiyaku Co., Ltd.
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小野 健司
Research Institute Daiichi Seiyaku Co. Ltd.
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佐野 光司
Research Institute Daiichi Seiyaku Co. Ltd.
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斎藤 董
Research Institute Daiichi Seiyaku Co. Ltd.
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諸井 黎明
Developmental Research Laboratories Daiichi Pharmaceutical Co. Ltd.
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Moroi R
Developmental Research Laboratories Daiichi Pharmaceutical Co. Ltd.
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