Studies on Seven-membered Ring Compounds. XXIII. Reactions of Tropylium Ions Having Fused Heterocyclic System with Various Amines
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概要
- 論文の詳細を見る
Reactions of tropylium ions having a fused heterocyclic system with various amines were examined. Reaction of 2-phenyloxazolotropylium monomethylsulfate (I) and 2-phenylthiazotropylium chloride (XXIV) with dimethylamine produced 2-phenyl-6-dimethylamino-6H-cycloheptoxazole (II) and 6-dimethylamino-2-phenyl-6H-cycloheptathiazole (XXV), respectively. Regarding the reaction with p-toluidine, both I and 1-p-tolyl-2-phenylimidazolotropylium chloride (XXVI) gave 1-p-tolyl-2-phenyl-1,6-dihydrocycloheptimidazole (VI) and 1-p-tolyl-2-phenyl-6-p-tolylimino-1,6-dihydrocycloheptimidazole (VII). Reaction of I with N-methylaniline produced 2-phenyl-6-p-methylaminophenyl-6H-cycloheptoxazole (XIX) and 2-phenyl-4-p-methylaminophenyl-4H-cycloheptoxazole (XX). From these results, it is concluded that the tropylium ions condensing a heterocycle has a priority for amination at C-6.
- 社団法人日本薬学会の論文
- 1967-05-25
著者
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渡辺 泰一郎
Chemical Research Laboratories Sankyo Co. Ltd.
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砂川 玄俊
Central Research Laboratories Sankyo Co. Ltd.
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相馬 信夫
Central Research Laboratories, Sankyo Co., Ltd.
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中沢 準一
Central Research Laboratories, Sankyo Co., Ltd.
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渡辺 泰一郎
Central Research Laboratories, Sankyo Co., Ltd.
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佐藤 良雄
Central Research Laboratories, Sankyo Co., Ltd.
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中沢 準一
Central Research Laboratories Sankyo Co. Ltd.
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相馬 信夫
Central Research Laboratories Sankyo Co. Ltd.
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佐藤 良雄
Central Research Laboratories Sankyo Co. Ltd.
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