Studies on Seven-membered Ring Compounds. XX. Reactions of Troponeimine Derivatives. (2)
スポンサーリンク
概要
- 論文の詳細を見る
The reaction of 2-methoxytroponeimine (I) and its N-methyl derivative (II) with active methylene compounds were carried out. The reaction of I with malononitrile, ethyl cyanoacetate or cyanoacetamide in the presence of sodium ethoxide afforded rearrangemet products, that is 3-phenylacrylic acid derivatives. The same reaction in the absence of sodium ethoxide gave mainly 2-imino-1,2-dihydrocyclohepta[b]pyrrole derivatives. However, the reaction of I with diethyl malonate afforded ethyl 2-oxo-8-methoxy-1,2-dihydrocyclohepta[b]pyrrole-3-carboxylate. II showed some different reactivity from I. Namely, the reaction of II with active methylene compounds in the presence of sodium ethoxide afforded 2-imino-1,2-dihydrocyclohepta[b]pyrrole derivatives besides rearrangement products.
- 社団法人日本薬学会の論文
- 1965-07-25
著者
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砂川 玄俊
Central Research Laboratories Sankyo Co. Ltd.
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相馬 信夫
Central Research Laboratories, Sankyo Co., Ltd.
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中尾 英雄
Research Laboratories, Sankyo Co., Ltd.
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相馬 信夫
Research Laboratories, Sankyo Co., Ltd.
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砂川 玄俊
Research Laboratories, Sankyo Co., Ltd.
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中尾 英雄
Sankyo Research Laboratories, Sankyo Co., Ltd.,
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中尾 英雄
Sankyo Research Laboratories Sankyo Co. Ltd.
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相馬 信夫
Central Research Laboratories Sankyo Co. Ltd.
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