Biochemical Studies on Benzoquinone Derivatives. III. Effects of Dihydroxythymoquinone on Rat Liver Mitochondria in the Electron Transport System.
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概要
- 論文の詳細を見る
Dihydroxythymoquinone (DTQ) showed a marked inhibitory action on State-3 respiration of rat liver mitochondria with succinate, whereas, State-4 respiration was not inhibited. This inhibition was neither released by 2,4-dinitrophenol nor other uncoupling agents. Completely DTQ inhibited oxidation of succinate by electron transport particles but the rate of inhibition was less than that of State-3 respiration by intact mitochondria. Reduction of cytochrome c by mitochondria with succinate was also inhibited. Succinate dehydrogenase was stimulated by DTQ.
- 公益社団法人日本薬学会の論文
- 1967-12-25
著者
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百瀬 和享
東北大学医学部薬学科
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小澤 光
Pharmaceutical Institute Tohoku University
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町田 征子
Pharmaceutical Institute, Tohoku University School of Medicine
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百瀬 和享
Pharmaceutical Institute, Tohoku University School of Medicine
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町田 征子
Pharmaceutical Institute Tohoku University School Of Medicine
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