Copper DL-Methionine, a New Anthelmintic for Swine Lung Worm. The Action of Copper DL-Methionine on Lung Worms.
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概要
- 論文の詳細を見る
Examination of various compounds effective aginst lung worm parasitic to swine and a great problem in dairy industry showed that copper DL-methionine is an effective agent, both from fundamental experiments and clinical test, and has little toxicity. In the present series of experiment, in vitro culture of the lung worms was attempted and anthelmintic effect of various compounds was tested by this in vitro culture, Copper (II) ion was found to be specifically effective. Copper (II) ion is absorbed through the digestive tract of the worm to become toxic and is not absorbed through the body surface. Effect of copper (II) ion is lowering of respiration and one of its reasons was thought to be the marked inhibition of succinic dehydrogenase action of the worms. The lung worm lives in the swine lung rich with oxygen and its oxygen consumption is great so that its inhibition proves lethal to the worm.
- 公益社団法人日本薬学会の論文
- 1962-10-25
著者
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小澤 光
Pharmaceutical Institute Tohoku University
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小澤 光
Department of Chemical Pharmacology, Tohoku University School of Medicine
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石関 忠一
Department of Chemical Pharmacology, Tohoku University School of Medicine
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新村 宗敏
Pharmaceutical Institute, Nihon University
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石関 忠一
Department Of Chemical Pharmacology Tohoku University School Of Medicine
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新村 宗敏
Pharmaceutical Institute Nihon University
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小澤 光
Department of Chemical Pharmacology, Pharmaceutical Institute, Tohoku University School of Medicine
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