EST analysis of genes that are expressed in the neural complex of Ciona intestinalis adults.
スポンサーリンク
概要
- 論文の詳細を見る
A subtractive cDNA library was made corresponding to mRNAs expressed in the neural complex relative to those expressed in the pharynx of adults of the ascidian Ciona intestinalis. Determination and comparison of expressed sequence tags (ESTs) of a set of 1,527 randomly selected clones demonstrated that they represent 832 independent sequences. Five hundred seventy-two of the clones contained amino-acid-encoding sequences. BLASTX analyses showed that 342 of the 572 clones were strong matches (P<10(-7)) to previously identified proteins, while the remaining 230 fell into the "no match" category. Among the clones matching previously identified proteins, about 80 clones represented proteins that are involved in the formation, maintenance of the structure, and function of the nervous system: 22 proteins are associated with signal transduction, five proteins are related to the synapse, 11 to transcription factors, nine to transporters, five to enzymes, and 13 to extracellular matrix and cytoskeletal components, and six to apoptosis. In addition, sequence information for genes associated with the immune system and for genes encoding proteins with interesting functions were obtained. These data provide cues for further studies on genes that are expressed in and function in the ascidian nervous system.
- 社団法人日本動物学会の論文
- 2001-12-10
著者
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SATOH Nori
Department of Zoology, Graduate School of Science, Kyoto University
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OKADA Taro
Department of Veterinary Pathology, Graduate School of Agricultural and Life Sciences, The Universit
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Okada Taro
Department Of Marine Biotechnology Faculty Of Engineering Fukuyama University
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OKA Nobuo
Department of Neurosurgery, Oka NeurosurgicaJ Hospital
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Okamoto Kenji
Department of Chemistry, Graduate School of Science, Kyoto University
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Okamoto Kenji
Department Of Applied Physics Osaka University
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Takamura Katsumi
Department of Marine Biotechnology, Faculty of Life Science and Biotechnology, Fukuyama University
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Akagi Akiko
Department of Marine Biotechnology, Faculty of Engineering, Fukuyama University
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Fukuoka Takuya
Department of Marine Biotechnology, Faculty of Engineering, Fukuyama University
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Hogaki Ayumu
Department of Marine Biotechnology, Faculty of Engineering, Fukuyama University
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Naito Dai
Department of Marine Biotechnology, Faculty of Engineering, Fukuyama University
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Oobayashi Yuji
Department of Marine Biotechnology, Faculty of Engineering, Fukuyama University
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Satoh Nori
Departmant Of Zoology Graduate School Of Science Kyoto University
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Naito Dai
Department Of Marine Biotechnology Faculty Of Engineering Fukuyama University
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Oka Nobuo
Department Of Marine Biotechnology Faculty Of Engineering Fukuyama University
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Akagi Akiko
Department Of Marine Biotechnology Faculty Of Engineering Fukuyama University
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Hogaki Ayumu
Department Of Marine Biotechnology Faculty Of Engineering Fukuyama University
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Oobayashi Yuji
Department Of Marine Biotechnology Faculty Of Engineering Fukuyama University
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Fukuoka Takuya
Department Of Marine Biotechnology Faculty Of Engineering Fukuyama University
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Takamura Katsumi
Department Of Marine Biotechnology Faculty Of Engineering Fukuyama University
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Takamura Katsumi
Department Of Biotechnology Faculty Of Engineering Fukuyama University
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Okamoto Kenji
Department Of Marine Biotechnology Faculty Of Engineering Fukuyama University
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