持続血液濾過(CHF)・持続血液濾過透析(CHDF)によるサイトカインの除去 : その機序および効果について

概要

論文の詳細を見る
We reviewed the removal of cytokines by continuous hemofiltration (CHF) and continuous hemodiafiltration (CHDF). The mechanisms of the processes are by convection (filtration), diffusion (dialysis) and adsorption. Removal by convection or diffusion is constant but it is small in amount. Removal by adsorption is more than that by convection or diffusion 2 to 4 h after starting CHF or CHDF, but its efficacy decreases later. But plasma cytokine levels.; did not change because the clearance of cytokines by CHF or CHDF is much smaller than its endogenous elimination. We concluded that the removal of cytokines by CHF or CHDF is not effective to decrease plasma cytokine levels and do not alter cytokine kinetics.
日本アフェレシス学会の論文
1999-02-28