QUANTITATIVE ULTRASTRUCTURAL CHANGES IN RAT PROLACTIN CELLS : RELATIONSHIP TO THE REBOUND IN SERUM PROLACTIN LEVELS AFTER BROMOCRIPTINE TREATMENT
スポンサーリンク
概要
- 論文の詳細を見る
Sprague-Dawley female rats were administered 10 mg/Kg of Bromocriptine by intubation daily for 3 weeks from 31 to 51 days of age. Tail blood was collected for RIA of PRL from meta- and di-estrus rats at the age of 51-55 days. Sampling was not repeated in any rat. A rebound incrcase in serum PRL levels occurred within 3 days after the cessation of subchronic treatment. Quantitative immunoclcctron microscopy using the protein A gold method was carried out in some pituitary tissues from the PRL-determined rats. Compared with the controls, excessive accumulation of higher gold-labeling mature secretory granules was found in PRL cells and also the Golgi complex was less developed in the treated rats just after the last intubation. The PRL cells exbibited more extrusion of secretory granules 2 days after the cessation when their ultrastructural features were almost completely restored. These data indicated that a rebound in serum PRL levels is accompanied by marked changes in the ultrastructural charactcristics of the PRL cells.
- 日本組織細胞化学会の論文
著者
-
螺良 愛郎
関西医科大学 第2病理
-
TSUBURA Airo
Department of Pathology II, Kansai Medical University
-
KATO Yuzuru
Department of Internal Medicine, Shimane Medical University
-
Oyaizu Naoki
Department Of Pathology Kansai Medical University
-
Oyaizu Naoki
関西医科大学 病理
-
Oyaizu Naoki
Department Of Clinical Laboratory Medicine Institute Of Medical Science University Of Tokyo
-
Oyaizu Naoki
Dept. Of Pathol. Kansai Medical University
-
Kato Yasuko
Department Of Anatomy Yamanashi Medical University
-
Kato Yuzuru
Department Of Medicine Shimane Medical University
-
Tsubura Airo
Kansai Medical Univ. Osaka Jpn
-
Tsubura Airo
関西医科大学 病理学第二
-
Tsubura Airo
Department Of Pathology 2 Kansai Medical University
-
MORII Sotokichi
Department of Pathology, Kansai Medical University
-
TOYODA TAKAAKI
Department of Pathology, Kansai Medical University
-
HARA FUMIO
Department of Pathology, Kansai Medical University
-
SAKAKI TOKUKO
Department of Pathology, Kansai Medical University
-
Kato Y
Department Of Pathology Tokyo Women's Medical University
-
螺良 愛郎
Department Of Pathology Ii Kansai Medical University
-
Tsubura A
Department Of Pathology Kansai Medical University
-
Kato Y
Tokyo Women's Medical Univ.
-
Hara F
Sci. Univ. Tokyo Tokyo Jpn
-
Hara Fumio
Department Of Pathology Kansai Medical University
-
Hara Fumio
Department Of Mechanical Engineering Faculty Of Engineering Science University Of Tokyo
-
Sakaki Tokuko
Department Of Pathology Kansai Medical University
-
Toyoda Takaaki
Department Of Pathology Kansai Medical University
-
Kato Yuzuru
Department Of Endocrinology Matabolism And Hematological Oncology School Of Medicine Shimane Univers
-
Morii Sotokichi
Department Of Pathology Kansai Medical School
-
Kato Yuzuru
Department Of Anesthesiology Yamagata Prefectural Nihonkai Hospital
-
Morii Sotokichi
Department Of Pathology Kansai Medica1 University
関連論文
- Eosinophilic cytoplasmic inclusions in papillary renal cell carcinoma
- Basal cell carcinoma arising from a keratinous cyst of the skin : a case report and review of the literature
- II-B-25 Nicotinamide regulates N-methyl-N-nitrosourea-induced photoreceptor cell apoptosis through poly (ADP-ribose) polymerase-1 signaling pathway in Sprague-Dawley rats(THE 45TH ANNUAL MEETING OF THE JAPAN SOCIETY OF HISTOCHEMISTRY AND CYTOCHEMISTRY)
- Malignant rhabdoid tumor of the liver : Case report and literature review
- Immunohistochemical profiles of Mallory body by a panel of anti-cytokeratin antibodies
- Serous microcystic adenoma (glycogen-rich cystadenoma) of the pancreas : Study of 11 cases showing clinicopathological and immunohistochemical correlations
- Hepatocellular Carcinoma with PIVKA-II Production in a Young Laboratory Monkey
- Mucinous carcinoma of the breast with neuroendocrine differentiation
- Time-specific occurrence of alopecia in neonatal C_BL mice treated with N-methyl-N-nitrosourea and the therapeutic efficacy of tacrolimus hydrate
- 22D-09-2 Mechanism of N-methyl-N-nitrosourea-induced photoreceptor cell apoptosis in SD rat : regulation of Bcl-2 family and caspase family.
- Latent Infection of Canine Herpes Virus in Laboratory Beagle Dogs
- Right intraventricular metastasis of squamous cell carcinoma of the uterine cervix : An autopsy case and literature review
- An autopsy case of hepatoid carcinoma of the ovary with PIVKA-II production : Immunohistochemical study and literature review
- Sjogren's syndrome in mice carrying the lpr^ gene and the therapeutic efficacy of an immunosuppressive agent FK506
- Age-specific and Dose-dependent Retinal Dysplasia and Degeneration Induced by a Single Intraperitoneal Administration of N-Methyl-N-nitrosourea to Rats
- Expression and localization of matrix metalloproteinases(MMPs)and tissue inhibitors of metalloproteinases(TIMPs)as prognostic factor in advanced colorectal carcinomas
- Juvenile hyaline fibromatosis : A report of two unrelated adult sibling cases and a literature review
- Expression of Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases in Gliomatosis Peritonei Derived from Ovarian Immature Teratoma
- Morphologic characteristics of N-methyl-N-nitrosourea-induced retinal degeneration in C_ BL mice
- Pigmentary degeneration induced by N-methyl-N-nitrosourea and the fate of pigment epithelial cells in the rat retina
- F-3 Living Salmonella administration induces an acute reduction in wheel-running activity via TLR5 but not TLR4 in mice(Free communication (Slide),8^ INTERNATIONAL SOCIETY OF EXERCISE AND IMMUNOLOGY SYMPOSIUM,ISEI2007 INFLAMMATION IN EXERCISE FRIEND O
- Late Progression After Sirolimus-Eluting Stent Implantation for de Novo Lesions : Comparison With Bare Metal Stent Implantation
- Impaired Compensatory Adaption to B-Cell Mass Reduction in Young Spontaneously Hypertensive Rats (SHR)
- Solitary fibrous tumor of soft tissue : a case report and immunohistochemical study
- A Study of Effect of CS-045, a New Antidiabetic Drug, on Hypertension in Spontaneously Hypertensive Rat
- An autopsy case of chronic progressive external ophthalmoplegia with renal insufficiency
- An autopsy case of pseudoxanthoma elasticum : histochemical characteristics
- Intrahepatic biliary epithelial cell damage and inflammation in portal tract in association with chronic colitis-harboring TCRα^ mice
- Digestion and Gastrointestinal Absorption of the 14-16-kDa Rice Allergens
- The effect on the rat spermatogenesis by Genistein
- N-Methyl-N-nitrosourea-induced Retinal Degeneration in Animals
- Apocrine adenocarcinoma of the eyelid with aggressive biological behavior : Report of a case
- Autopsy case of desminopathy involving skeletal and cardiac muscle
- An autopsy case of primary mixed choriocarcinoma and mature teratoma located in the thymic region associated with elevated human chorionic gonadotropin levels and characteristic testicular changes
- Multistep mouse mammary tumorigenesis through preneoplasia to neoplasia and acquisition of metastatic potential
- Primary Pulmonary Artery Sarcoma
- Pyodermia Chronica Glutealis Complicated by Acromegalic Gigantism
- Time-specific action of N-methyl-N-nitrosourea in the occurrence of retinal dysplasia and retinal degeneration in neonatal mice
- Immunohistochemical Observations on Human Testicular Tissues
- Fas-independent Apoptosis of Photoreceptor Cells in C_3H Mice
- QUANTITATIVE ULTRASTRUCTURAL CHANGES IN RAT PROLACTIN CELLS : RELATIONSHIP TO THE REBOUND IN SERUM PROLACTIN LEVELS AFTER BROMOCRIPTINE TREATMENT
- IMMUNOHISTOCHEMICAL STUDIES ON HUMAN BREAST TISSUES WITH ANTIBODIES AGAINST MOUSE MAMMARY TUMOR VIRUS CORE PROTEIN
- SENSITIVE IMMUNOHISTOCHEMICAL DEMONSTRATION OF ENDOGENOUS PROLACTIN IN MAMMARY GLAND AND DMBA-INDUCED MAMMARY CARCINOMA OF RATS BY ABC METHOD
- Influence of Fixative Procedures on Immunohistochemical Detection of Mammary Tumor Virus (MTV) Antigens in Mice
- Immunohistochemical Detection of Prolactin in Mammary Gland and its Cancer of Adult Female Rats
- IMMUNOHISTOCHEMICAL LOCALIZATIONS OF ALPHA-LACTALBUMIN IN HUMAN BREAST LESIONS IN RELATION TO SECRETORY ACTIVITY
- HISTOCHEMICAL OBSERVATIONS ON ENZYMES IN PREGNANCY-DEPENDENT MAMMARY TUMORS OF GRS/A MICE
- Cytochemical Identifications of Leukemic Cells in Autopsy Materials
- DEHYDROGENASES IN LOCAL CARCINOGENESIS IN RAT MAMMARY GLAND BY DUSTING OF DMBA-POWDER
- Ultracytochemical Observation on Fat Granules in Pregnant Mammary Gland, Using of Lipase-Digestive Method for Triglycerides
- HISTO- AND BIOCHEMICAL STUDIES ON DEHYDROGENASES IN TUMORIGENESIS IN RAT ZYMBAL GLANDS INDUCED WITH DMBA AND DAS
- IMMUNOHISTOCHEMICAL REACTIVITY OF A MONOCLONAL ANTIBODY AGAINST CELL MEMBRANES OF HUMAN MAMMARY CARCINOMA CELLS (125B4) WITH RAT NORMAL TISSUES AND DMBA-INDUCED MAMMARY TUMORS
- Inhibitory Effect of the Angiogenesis Inhibitor O-(Chloroacetyl-carbamoyl) fumagillol (TNP-470) on Tumor Growth and Metastasis of Murine Mammary Tumor Cell Line (JYG-B) Inoculated in Female Nude Mice
- Degradation of Soluble Proteins Including Some Allergens in Brown Rice Grains by Endogenous Proteolytic Activity during Germination and Heat-Processing
- Pathological Finding of Sirolimus-Eluting Stent (SES) Restenosis Lesion With Black Hole Appearance on Intravascular Ultrasound
- OE-015 Impact of Chronic Kidney Disease and Diabetes on Long-Term Prognosis in Patients with Primary Angioplasty for Acute Coronary Syndrome(Acute coronary syndrome, basic/clinical(01)(IHD),Oral Presentation(English),The 72nd Annual Scientific Meeting of
- Protein-bound crotonaldehyde accumulates in the spinal cord of superoxide dismutase-1 mutation-associated familial amyotrophic lateral sclerosis and its transgenic mouse model
- Intracellular binding of fukutin and α-dystroglycan : Relation to glycosylation of α-dystroglycan
- WS1-3 Accumulation of protein-bound crotonaldehyde in the spinal cord of a transgenic mouse model of amyotrophic lateral sclerosis(THE 46TH ANNUAL MEETING OF THE JAPAN SOCIETY OF HISTOCHEMISTRY AND CYTOCHEMISTRY)
- Unique astrocytic inclusion in a 2 month-old baby showing Leigh-like brain lesions with lactic acidosis
- P-39 Continuous expression of c-jun and c-fos oncogene in developmental stage of rat brain
- Early stage of human adenovirus type 12-inoculated retinal tissue of F344 newborn rat
- Immunohistochemical Studies on Repopulation of Leydig Cells after Ethanedimethanesulfonate-injury in Bilaterally Cryptorchid Rats
- Quantitative ultrastructural changes in rat prolactin cells : Relationship to the rebound in serum prolactin levels after Bromocriptine treatment.
- Immunohistochemical detections of secretory component in human normal mammary gland and breast cancer
- Angiosarcoma of the Breast: Immunohistochemical Demonstration of Steroid Receptors and Literature Review
- Serum Levels of 20 Kilodalton Human Growth Hormone (20K-hGH) in Patients with Acromegaly before and after Treatment with Octreotide and Transsphenoidal Surgery
- Apoptotic Changes Precede Mitochondrial Dysfunction in Red Cell-type Pyruvate Kinase Mutant Mouse Erythroleukemia Cell Lines
- A Double Immunohistochemistry for Endogenous Prolactin and Incorpoarted BrdU in Mannary Glands of Virgin Rats Exposed to Serum Prolactine Fluctation
- A DOUBLE IMMUNOHISTOCHEMISTRY FOR ENDOGENOUS PROLACTIN AND INCORPORATED BROMODEOXYURIDINE IN RAT MAMMARY GLAND TISSUES
- Delayed visual loss following massive hemorrhage during left pneumonectomy : a case report
- F-22 The different effects of exhaustive exercise on poly I:C-induced IFN-β and TNF-α productions in mice(Free communication (Slide),8^ INTERNATIONAL SOCIETY OF EXERCISE AND IMMUNOLOGY SYMPOSIUM,ISEI2007 INFLAMMATION IN EXERCISE FRIEND OR FOE?)
- Osteopontin Expression May Be Induced by c-Src in Papillary Thyroid Carcinoma
- Osteopontin Expression in Papillary Thyroid Carcinoma
- A-35 Electron microscopic replica immunostaining analysis of splenic AA amyloid fibrils in serum amyloid P (SAP) component-deficient mice
- Immunohistochemical Study of Splenic Amyloid Deposits in Serum Amyloid P Component(SAP)-deficient Mice.
- Dystrobrevin localization in various ocular tissues and cerebellum of rats revealed by immunoelectron microscopy
- Scanning electron microscopic study of erythrocyte shapes artificially jetted through tubes at different pressures by 'in vitro cryotechnique for erythrocytes'
- Scanning electron microscopic study of flowing erythrocytes in hepatic sinusoids as revealed by 'in vivo cryotechnique'
- Acromegaly Associated with Monoclonal Gammopathy of Undetermined Significance (MGUS)
- Molecular biological approaches to neurological disorders including knockout and transgenic mouse models
- Immunohistochemical Observations on Locally Induced Tumors with Direct Application of DMBA-powder onto Rat Mammary Fatty Tissues
- Effect of tetrahydrobiopterin on nitric oxide synthase-containing cells in the rat hippocampus
- Involvement of nitric oxide in glucose toxicity on differentiated PC12 cells : prevention of glucose toxicity by tetrahydrobiopterin, a cofactor for nitric oxide synthase
- An adult case of Henoch-Schonlein purpura complicating common peroneal nerve mononeuropathy
- The first isolation of Nocardia nova from an HIV-1 infected individual in Japan
- Glomeruloid hemangioma
- Disseminated coccidioidomycosis with intra- and paravertebral abscesses
- Mycobacterium haemophilum infection in a Japanese patient with AIDS
- A Case of Contact Urticaria from Hydroxypropyltrimonium Hydrolyzed Collagen
- Epidermal cyst with pilomatricoma (follicular hybrid cyst) : Immunohistochemical study with epithelial keratins and filaggrin
- Impact of ω-5 Gliadin on Wheat-Dependent Exercise-Induced Anaphylaxis in Mice
- Fukutin expression in mouse non-muscle somatic organs : its relationship to the hypoglycosylation of α-dystroglycan in Fukuyama-type congenital muscular dystrophy
- Chronological Expression and its Significance of c-jun and c-fos mRNA in Rat Brain
- Ovomucoid Rendered Insoluble by Heating with Wheat Gluten but not with Milk Casein
- Baby Composition Assessed by Bioelectrical Impedance Analysis (BIA) in Patients with Graves' Disease Before and After Treatment
- 免疫組織化学的診断における抗原賦活法の有用性について
- Shigella sonnei Outbreak among Men Who Have Sex with Men in Tokyo
- Diabetes Accelerates Osteoporosis in Stroke Prone Spontaneously Hypertensive Rats
- 乳癌におけるレクチン結合能と転移形性能に関する検討