A Case of Biphasic Pulmonary Blastoma

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Background: Biphasic Pulmonary blastoma is a rare disease. On the basis of mesenchymal components, this tumor was classified into high-grade adenocarcinoma of fetal lung type(H-FLAC)and low-grade adenocarcinoma of fetal lung type(L-FLAC). Case: A 69-year-old woman had a cough, shortness of breath, and dyspnea in December 1994, and these symptoms gradually worsened. A local physician found an abnormal shadow on a chest radiogram in April 1995, and the patient was subsequently admitted to our hospital. A computed tomographic scan of the chest revealed a solid tumor in S^6 of the left lung. Histopathological examination of a specimen obtained by transbronchial biopsy showed evidence of malignancy, but a definitive diagnosis could not be established. The tentative diagnosis was a primary malignant tumor of the lung, and a left pneumonectomy was performed in June 1995, Pathological examination, including immunohistochemical analysis, suggested a biphasic Pulmonary blastoma, which had an epithelial component of high-grade adenocarcinoma of fetal lung type. Conclusion: We describe a case of biphasic pulmonary blastoma associated with H-FLAC epithelial components.
日本肺癌学会の論文
2001-04-20